MINI REVIEW article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1617410
Effects of gut microbiota in breast cancer
Provisionally accepted
- 1Ziyang People's Hospital, Ziyang, China
- 2The First People’s Hospital Ziyang, Sichuan, China
- 3Yanjiang District People's Hospital of Ziyang, Ziyang, China
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Breast cancer (BC) stands as the predominant form of cancer affecting women globally, with its etiology rooted in a complex interplay of factors. Emerging research underscores the significant impact of microbiota on the development of BC. Evidence points to a correlation between BC and microbial imbalance, not only within the intestinal milieu but also in breast tissue itself. Alterations in the diversity and functionality of bacterial populations in these areas are implicated in the disease's pathogenesis.The intestinal microbiota exerts a pivotal influence on the metabolism of steroid hormones, including estrogens, which are recognized as critical elements in the risk profile for BC, particularly among women who have reached menopause.These hormones can drive the onset and advancement of BC via multiple mechanisms.Concurrently, a body of research highlights the contributory roles of immune system elements, inflammatory processes, dietary patterns, and the use of probiotics in the context of BC. Understanding this intricate interplay holds promise for developing innovative therapeutic approaches
Keywords: breast cancer, Gut Microbiota, Prebiotics, probiotic, dysbiosis Introduce
Received: 24 Apr 2025; Accepted: 13 May 2025.
Copyright: © 2025 Li, Chen, He and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Junchuan Li, Yanjiang District People's Hospital of Ziyang, Ziyang, China
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