ORIGINAL RESEARCH article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1617613
Global, regional, and national larynx cancer burden and health inequality analysis from 1990 to 2021 with a prediction from 2022 to 2040
Provisionally accepted
- Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Laryngeal cancer imposes a substantial global health burden. This study analyzed Global Burden of Disease data from 1990 to 2021 to assess prevalence, incidence, mortality, and disability-adjusted life years, and projected trends to 2040. Results show considerable regional variation, with higher incidence in high socio-demographic index regions and greater mortality and disability in middle-low index regions. Central Europe and the Caribbean experienced the highest burdens.Over time, health inequalities have improved, but disparities persist. The overall burden is expected to decline by 2040, highlighting the need for equitable resource allocation, improved healthcare access, and targeted public health interventions to reduce disparities.
Keywords: Global burden of disease, social-demographic index, Bayesian age-period-cohort, risk factor, Laryngeal cancer (LC)
Received: 24 Apr 2025; Accepted: 30 Jun 2025.
Copyright: © 2025 Jiang, Xia and Yao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Junjie Jiang, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.