CASE REPORT article
Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1624498
This article is part of the Research TopicCurrent Challenges and Future Perspectives in Neuro-Oncological ImagingView all 5 articles
Postoperative Microcystic Meningioma of the Fourth Ventricle with Subsequent Giant Cell Reparative Granuloma: A Case Report
Provisionally accepted
- 1Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
- 2Department of Radiology, The First Affiliated Hospital, Three Gorges University School of Medicine, Yichang, China, Yichang, China
- 3Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Hangzhou, China
- 4Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Hangzhou, China
- 5Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Hangzhou, China
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Background: Microcystic meningioma (MM) is a distinctive benign tumor typically located in the supratentorial region. Giant cell reparative granuloma (GCRG) is another rare reactive benign lesion associated with surgical trauma or tissue injury. The occurrence of MM in the fourth ventricle is extremely uncommon, and the development of GCRG following cranial tumor surgery is rare. Case report: We present a case of MM extending into the fourth ventricle in a 54-year-old man. The initial diagnosis was based on magnetic resonance imaging (MRI), and the tumor was successfully treated with surgery. Postoperative histopathological analysis confirmed the diagnosis of MM. However, a mass was detected at the original surgical site during a followup examination one year later. Combined preoperative imaging and postoperative pathology confirmed the final diagnosis of giant cell reparative granuloma (GCRG). Conclusion: In cases of MM at atypical locations and GCRG, an imaging-based differential diagnosis is crucial for guiding treatment decisions and predicting prognosis. Regular postoperative reviews are also essential for detecting complications.
Keywords: Microcystic meningioma, Giant cell reparative granuloma, Magnetic Resonance Imaging, Fourth Ventricle, case report
Received: 07 May 2025; Accepted: 09 Jul 2025.
Copyright: © 2025 Xu, Fu, Li, Dong, Tang, Wang and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Chongran Sun, Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Hangzhou, China
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