CASE REPORT article
Front. Oncol.
Sec. Cardio-Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1634106
This article is part of the Research TopicCase Reports in Cardio-Oncology: 2025View all 6 articles
Primary intravenous synovial sarcoma in the proximal great vein: A case report and literature review
Provisionally accepted
- Ganzhou People's Hospital, Ganzhou, China
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Primary intravenous synovial sarcoma (PISS) is an extremely rare disease originating from pluripotent mesenchymal stem cells, and has the potential to develop in nearly any part of the body. This report describes the case of a 54-year-old man who presented with a 20-day history of neck and facial swelling. Imaging findings on contrast-enhanced CT and 18F-FDG PET/CT revealed filling defects with markedly increased FDG uptake with involvement of multiple venous structures, including the superior vena cava, brachiocephalic vein, and left internal jugular vein, and enlarged lymph nodes near the aortic arch. A vascular interventional biopsy confirmed PISS. Here, we discuss the clinical characteristics and imaging findings of PISS and review 14 cases reported in previous studies.
Keywords: primary, intravenous synovial sarcoma, proximal great vein, 18F-FDG PET/CT, case report
Received: 23 May 2025; Accepted: 26 Aug 2025.
Copyright: © 2025 Tang, Wu, Huang and Wei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiawang Wei, Ganzhou People's Hospital, Ganzhou, China
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