CASE REPORT article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1638365
Trichiasis as a Clinical Manifestation of Subconjunctival Epithelioid Hemangioendothelioma: A Rare Case Report
Provisionally accepted
- Chengdu Third People's Hospital, Chengdu, China
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Epithelioid hemangioendothelioma(EHE) is a rare, low-grade malignant tumor of vascular endothelial origin, commonly found in the lungs, liver, bones, and soft tissue.However, orbital involvement is uncommon. This study presents a rare case of EHE located in the orbit and confined to the subconjunctival space which has not been previously documented. An elderly male patient presented with a six-month history of discomfort in his left eye, initially diagnosed with lower eyelid trichiasis and scheduled for surgical intervention. A detailed examination identified a purplish, spherical mass beneath the fornix conjunctiva of the left lower eyelid. Computed tomography (CT) imaging of the orbit revealed a well-defined soft tissue mass beneath the left globe, adjacent to the inferior rectus muscle, with no evidence of invasion into the orbital cavity. Ultrasound showed a hypoechoic mass with abundant internal vascularity. Following complete surgical excision, histopathological analysis confirmed the diagnosis of EHE. Postoperative follow-up revealed no signs of recurrence, with full resolution of the trichiasis. No eye movement disorders or visual abnormalities were observed. Despite its generally low malignancy, EHE carries a risk of recurrence and metastasis. Complete excision is crucial to minimize recurrence risk, and long-term follow-up is essential for optimal management.
Keywords: Epithelioid hemangioendothelioma, Orbit, Trichiasis, Subconjunctival mass, Surgical excision, histopathological diagnosis
Received: 30 May 2025; Accepted: 18 Aug 2025.
Copyright: © 2025 Hu, Wang, Zhou, Chen, Luo, Guo, Wang and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yi Sun, Chengdu Third People's Hospital, Chengdu, China
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