CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1640018
This article is part of the Research TopicLiver Diseases – From Pathophysiology to New Treatment OptionsView all 3 articles
Concurrent Two Adenomatoid Tumors of Liver: A Case Report
Provisionally accepted
- 1Shandong Provincial Hospital, Jinan, China
- 2Linyi People's Hospital, Linyi, China
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A 40-year-old man with two accidentally discovered subcapsular liver tumors was admitted to our hospital for further treatment. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed two hypervascular lesions, which showed marked enhancement in arterial phase and prolonged enhancement in portal venous phase. The patient had not received any prior treatment, and the two lesions were pathologically confirmed after partial hepatectomy. Hematoxylin-eosin staining revealed a partially cystic, highly vascular, and well-encapsulated neoplasm.Immunohistochemistry findings demonstrated that the epithelioid tumor cells were positive for vimentin, calretinin, cytokeratin, CD 31, CD 34, which supported their mesothelial origin. Immunohistochemistry for a mesothelial marker should be performed for determining the presence of an adenomatoid tumor when benign epithelioid cells are seen.
Keywords: Adenomatoid Tumor, Liver, computed tomography, Magnetic Resonance Imaging, case report
Received: 03 Jun 2025; Accepted: 13 Aug 2025.
Copyright: © 2025 Bi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lei Bi, Shandong Provincial Hospital, Jinan, China
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