CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1642467
This article is part of the Research TopicReal-World Clinical and Translational Research in Gastrointestinal CancersView all 12 articles
Carcinosarcoma of the Common Bile Duct: A Rare Case Report with Literature Review
Provisionally accepted
- 1Inner Mongolia Medical College, Hohhot, China
- 2Inner Mongolia Autonomous Region People's Hospital, Hohhot, China
- 3Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
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Carcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile duct. The patient underwent successful radical pancreaticoduodenectomy, and postoperative histopathological analysis confirmed carcinosarcoma with predominant sarcomatoid differentiation. This report underscores the diagnostic challenges and therapeutic considerations for this rare entity, emphasizing the critical role of pathological confirmation.
Keywords: Carcinosarcoma, Common Bile Duct, Pancreaticoduodenectomy, Sarcomatoid differentiation, prognosis
Received: 06 Jun 2025; Accepted: 31 Jul 2025.
Copyright: © 2025 Lou, Hu, Liu, A and Fang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhi-wei Hu, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China
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