ORIGINAL RESEARCH article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1644295
Reconstruction Strategies for Extensive Bone Defects Following Resection of Primary Malignant Tumors in the Distal Radius
Provisionally accepted
- 1The Second Affiliated Hospital of Zhejiang University, Hangzhou, China
- 2Yunhe County People's Hospital, LiShui, China
- 3University of Technology Sydney, Sydney, Australia
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Background: This study aimed to evaluate surgical resection techniques for primary malignant tumors of the distal radius and to examine the reconstruction strategies employed for resulting large bone defects. Methods: A retrospective analysis was conducted on 11 cases involving the resection and reconstruction of primary malignant tumors in the distal radius. Complete medical records and follow-up data from December 2013 to December 2022 were reviewed. Oncological outcomes were assessed, with specific focus on the extent of tumor invasion, surgical resection techniques, and reconstruction strategies. Results: The follow-up period ranged from 5 to 118 months, with a mean duration of 41.6 months. At the final follow-up, local recurrence was observed in three patients, six died due to disease progression, and five were alive. For tumors confined to the distal radius, resection of the distal radius follow by joint-preserving reconstruction using either autologous fibular grafts or 3D-printed prostheses .For tumors involving the distal radius, proximal carpal bones, and/or distal ulna, wrist arthrodesis are chosed using either autologous fibular grafts or ipsilateral ulnar transposition with arthrodesis For tumors involving more than half of the distal radius, reconstruction strategies include ulnar-only fixation or wrist arthrodesis with ipsilateral ulnar transposition.. Conclusions Primary malignant tumors of the distal radius are rare and associated with a poor prognosis. Selection of resection and reconstruction techniques is primarily influenced by the extent of tumor invasion, with joint-preserving strategies feasible in selected cases and arthrodesis required for more extensive bone involvement.
Keywords: Bone defect, Distal radius, malignancy, reconstruction, resection
Received: 10 Jun 2025; Accepted: 29 Sep 2025.
Copyright: © 2025 Guo, Wang, Yang, Qiu, Wu, Wang, Tao and Ye. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: ZhengMing Yang, yangzhengmingyzhm@126.com
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