SYSTEMATIC REVIEW article
Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1646187
This article is part of the Research TopicInnovative Approaches in Glioma Therapy: Exploring New Therapeutic Frontiers- Volume IIView all articles
A Scientometric Analysis of Global Research on Gut Microbiota and Glioma
Provisionally accepted
- Northwest University First Hospital, Xi'an, China
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Most previous studies have demonstrated that gut microbiota is closely related to the prognosis of glioma. However, there is currently no corresponding bibliometric analysis to systematically review, analyze, and visualize prior research. This study focused on 127 publications obtained from the Web of Science Core Collection and conducted correlation analyses of authors, journals, institutions, countries, keywords, and citations using VOSviewer, CiteSpace, and the R package The results indicate that China and the United States are the leading countries conducting research in this field. The Anderson Cancer Center at the University of Texas in the United States and Central South University in China are the primary research institutions. Recent studies suggest that the regulation of the brain-gut axis between gut microbiota and glioma remains a prominent research hotspot, while the anti-cancer mechanisms of the enteric nervous system and gut microbiota have emerged as significant topics in recent years. Furthermore, the receptor tyrosine kinase pathway is expected to provide extensive research opportunities in the future. This article systematically reviews the current research status and hotspots of gut microbiota in glioma for the first time, conducts a visual analysis, and explores research trends and future directions.
Keywords: Glioma, Gut Microbiota, Bibliometrics, VOSviewer, Citespace
Received: 13 Jun 2025; Accepted: 22 Sep 2025.
Copyright: © 2025 Chen, Shu, Zhang and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiao Zhao, zhaojiao202506@163.com
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