CASE REPORT article
Front. Oncol.
Sec. Gynecological Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1647366
This article is part of the Research TopicCutting-Edge Strategies in Screening, Prevention, and Treatment in Gynaecologic OncologyView all 12 articles
Cervical Cancer Masquerading as Ovarian Tumor: Diagnostic Challenges in a Case with Severe Pyometra-Pyocolpos Complex
Provisionally accepted
- 1Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, China
- 2China Academy of Chinese Medical Sciences Wangjing Hospital, Beijing, China
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Early-stage cervical cancer, which is often asymptomatic, presents considerable diagnostic difficulties when accompanied by vaginal adhesions that conceal malignant lesions. In this report, we describe an exceptionally rare case of cervical cancer complicated by extensive pyometra and pyocolpos, highlighting key diagnostic challenges and evidence-based treatment approaches.Clinical discussion:The coexistence of cervical cancer complicated by extensive pyometra and pyocolpos is a rare clinical condition that requires a comprehensive multidisciplinary diagnostic approach. For such complex presentations, a tripartite protocol-combining imaging continuity assessment, postdrainage cytomorphologic analysis, and histopathologic verification-is essential to circumvent diagnostic delays and sampling errors.①Postmenopausal pyometra cannot be excluded as a complication of gynecologic malignancies.High-grade squamous intraepithelial lesion (HSIL) and squamous cell carcinoma antigen (SCC) can directly extend proximally into the uterus. The most common clinical manifestations include pyometra and cervical stenosis. Emphasis should be placed on early detection and prevention of this condition.
Keywords: Cervical carcinoma, Pyometra, Vaginal adhesions, case report, postmenopausal women, Squamous cell carcinoma, Misdiagnosis
Received: 15 Jun 2025; Accepted: 29 Jul 2025.
Copyright: © 2025 Xie, Liu, Huang, Zhao, Qiu, Liu and Mao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dongwei Mao, Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, China
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