CASE REPORT article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1651824
Opportunities and challenges of radiofrequency ablation for substernal goiter
Provisionally accepted
- 1Department of Ultrasound Medicine, Gansu Provincial Hospital, Lanzhou, China
- 2First Clinical Medical School, Gansu University of Chinese Medicine, Lanzhou, China
- 3Gansu University of Chinese Medicine, Lanzhou, China
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Substernal goiter (SG) refers to an enlargement of the thyroid gland that extends below the sternal notch or clavicle. whileWhile most cases are benign, a few may be malignant. Surgical resection is the standard treatment for SGs that cause clinical symptoms. This case report presents a 60-year-old female SG patient with a history of thyroidectomy and congenital vascular anomalies, who developed symptoms including significant airway compression and difficulty swallowing liquids. Flowing Following a detailed imaging and pathologic evaluation, ultrasound-guided radiofrequency ablation was performed according to the patient's wishespathological evaluation, ultrasound-guided radiofrequency ablation was performed at the patient's request. The procedure was successful and led to a favorable clinical outcome. This case highlights a potential alternative treatment approach for patients with SG, particularly those for whom surgery may pose additional risks.
Keywords: Substernal goiter, Vascular dysplasia, Radiofrequency ablation, intervention, efficacy
Received: 22 Jun 2025; Accepted: 24 Jul 2025.
Copyright: © 2025 Han, Feng and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Nan Wang, Department of Ultrasound Medicine, Gansu Provincial Hospital, Lanzhou, China
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