CASE REPORT article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1654218
This article is part of the Research TopicRecent Trends and Advancements in Multispectral and Hyperspectral Imaging for Cancer DetectionView all 8 articles
Primary adrenal melanoma with extensive metastasis：A case report and literature review
Provisionally accepted
- 1Department of Radiology, Second Hospital of Tianjin Medical University, Tianjin, China
- 2Second Affiliated Hospital of Soochow University Department of Radiology, Suzhou, China
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Primary adrenal melanoma is an exceedingly rare diagnosis. We present a new case of primary left adrenal melanoma with rapid and extensive distant metastasis.The patient underwent a left adrenal tumor biopsy and the pathology result showed an adrenal malignant melanoma. Immunohistochemical staining showed positive antibody-specific cytoplasmic reaction to Melan A, HMB45 and SOX-10. We reviewed the relevant cases that have been reported in the published English literature and discussed the diagnostic criteria, differential diagnosis and possible management.
Keywords: adrenal gland, Melanoma, diagnosis, metastasis, primary
Received: 26 Jun 2025; Accepted: 15 Jul 2025.
Copyright: © 2025 Guo, Shi, Li, Liu and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guoping Xu, Department of Radiology, Second Hospital of Tianjin Medical University, Tianjin, China
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