CASE REPORT article
Front. Oncol.
Sec. Genitourinary Oncology
This article is part of the Research TopicUrothelial Neoplasms: An Integrated Approach to Prevention, Diagnostics, and Personalized TherapyView all 15 articles
Collision metastasis in a pelvic lymph node from urothelial and prostatic carcinoma: a rare case report and literature review
Provisionally accepted
- 1Department of Urology, Yuyao People's Hospital, Ningbo, China
- 2Comprehensive Genitourinary Cancer Center, The First Affiliated Hospital of Ningbo University, Ningbo, China
- 3Department of Pathology, Yuyao People's Hospital, Ningbo, China
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Metastasis of both urothelial carcinoma and prostatic carcinoma to the same lymph node is extremely rare. We report a case of collision metastasis involving bladder urothelial carcinoma and prostatic adenocarcinoma in a 76-year-old male. The patient underwent laparoscopic radical cystoprostatectomy and bilateral pelvic lymph node dissection. Final pathological examination revealed high-grade urothelial carcinoma (pT2bN1M0) and prostatic adenocarcinoma (pT2N1M0, Gleason score 4 + 4 = 8). Notably, coexisting metastatic foci of urothelial carcinoma and prostatic adenocarcinoma were identified within a single pelvic lymph node. During the 18-month postoperative follow-up, the patient developed multifocal hepatic and bone metastases. Collision metastasis is a rare clinical event with complex prognostic implications. This study aims to enhance understanding of this 2 unique pathological entity and provide clinical references for the management of such cases through case analysis and literature review.
Keywords: Collision metastasis, urothelial carcinoma, Prostatic adenocarcinoma, liver metastasis, bone metastasis
Received: 02 Jul 2025; Accepted: 20 Nov 2025.
Copyright: © 2025 Shi, Zheng, Ma, Sheng, Wei, Chen and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xu-Dong Zheng, zxd0235@163.com
Qi Ma, fyymaqi@nbu.edu.cn
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