There was a mistake in Figure 5 as published. In the originally published version, Figure 5C was inadvertently duplicated from Figure 3C. The corrected Figure 5 and its caption appear below.
There was a mistake in the caption of Figure 1 as published. The descriptions for Figure 1A and Figure 1B were inadvertently reversed. It was mistakenly written as “(A) PCR analysis shows that PTBP1 is significantly overexpressed in colorectal cancer tissues compared to adjacent normal tissues. (B) Western blot analysis confirming the elevated expression of PTBP1 in CRC tissues. Representative images are shown.”. The corrected caption of Figure 1 appears below.
Figure 1
Figure 5
“Figure 1. PTBP1 expression is elevated in colorectal cancer and reduced by curcumin. (A) Western blot analysis confirming the elevated expression of PTBP1 in CRC tissues. Representative images are shown. (B) PCR analysis shows that PTBP1 is significantly overexpressed in colorectal cancer tissues compared to adjacent normal tissues. (C) RNA sequencing data from GSE229613 indicates that curcumin treatment significantly reduces PTBP1 expression in colorectal cancer cells. (D) Target prediction analysis identifies CDK2 as a potential target of curcumin. Note: ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.”
In the Methods section, we described procedures for immunohistochemistry (IHC); however, no IHC results are presented or discussed in the article. This was an oversight. IHC was originally planned as part of the experimental design, but the data were not included in the final manuscript.
A correction has been made to the section Methods, Immunohistochemistry for Ki67:
“Paraffin-embedded tumor tissue sections were deparaffinized in xylene and rehydrated through a graded ethanol series. Antigen retrieval was performed by heating the sections in a citrate buffer (pH 6.0) at 95°C for 10 minutes. After cooling, sections were incubated with 3% hydrogen peroxide for 10 minutes to block endogenous peroxidase activity. The sections were then blocked with 5% BSA for 30 minutes at room temperature and incubated overnight at 4°C with a primary antibody against Ki67. After washing, sections were incubated with a secondary antibody conjugated to HRP for 1 hour at room temperature. Color development was achieved using DAB, and sections were counterstained with hematoxylin. After dehydration and clearing, coverslips were mounted, and staining was evaluated under a light microscope. Ki67-positive nuclei were quantified under a light microscope.”
The original version of this article has been updated.
Statements
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
Curcumin, colorectal cancer, PTBP1, CDK2, autophagy the effects of curcumin on crc cell viability, proliferation, migration, invasion
Citation
Zheng H, Li S, Wang Y, Su S, Wang Y and Wang F (2025) Correction: Curcumin inhibits colorectal cancer progression by targeting PTBP1 and CDK2-mediated pathways. Front. Oncol. 15:1659429. doi: 10.3389/fonc.2025.1659429
Received
07 July 2025
Accepted
22 August 2025
Published
02 September 2025
Volume
15 - 2025
Edited and reviewed by
Guanmin Jiang, The Fifth Affiliated Hospital of Sun Yat-sen University, China
Updates
Copyright
© 2025 Zheng, Li, Wang, Su, Wang and Wang.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Fujing Wang, 202301481@hrbmu.edu.cn
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.