ORIGINAL RESEARCH article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1661727
This article is part of the Research TopicAdvancements in Targeted Neoadjuvant and Adjuvant Therapies for Drug-Resistant Breast CancersView all 3 articles
Evaluation of real-world follow-up methods and their association with adherence and safety in adjuvant breast cancer therapy: A retrospective study
Provisionally accepted
- 1Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China
- 2Hebei Key Laboratory of Cancer Radiotherapy and Chemotherapy, Baoding, China
- 3Teaching Office, Affiliated Hospital of Hebei University, Baoding, China
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Aim To compare the associations between different follow-up management methods—telephone, WeChat, and mini-program—and treatment compliance, safety, quality of life, and self-management in breast cancer patients receiving adjuvant therapy. Methods This retrospective study reviewed clinical and follow-up records of patients with newly diagnosed breast cancer who underwent adjuvant therapy after radical surgery. Based on documented follow-up modes, patients were categorized into three groups: telephone, WeChat, and the “Doctor Haixin” mini-program. Key clinical indicators, including treatment adherence, quality of life, adverse events, and self-management levels, were extracted from medical records and patient-reported follow-up data collected over a 12-week period. Results Patients in the mini-program group were found to have higher recorded adherence rates and better self-reported outcomes in quality of life and self-management compared with the telephone and WeChat groups. All groups showed improved quality of life over time, while adverse event rates remained comparable across groups. Conclusion Among patients retrospectively assessed, those managed via the mini-program follow-up exhibited more favorable patterns in adherence and patient-reported outcomes. These findings suggest that digital platforms may be associated with enhanced care quality in the context of breast cancer follow-up.
Keywords: breast cancer, treatment compliance, Digital follow-up, self-management, patient-reported outcomes
Received: 08 Jul 2025; Accepted: 08 Sep 2025.
Copyright: © 2025 Li, Zhang, Yang, Li, Tian, Li, Ren and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qian Zhang, Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China
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