CASE REPORT article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1663104
NUTM1-rearranged lung sarcoma: A rare case imaged with dynamic and static 18F-FDG PET/CT
Provisionally accepted
- 1National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
- 2Tongji University Dongfang Hospital, Shanghai, China
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Background: Nuclear protein of testis midline carcinoma family member 1 (NUTM1)-rearranged lung sarcomas are rare malignant malignancies. 18F-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT) is widely used for the differential diagnosis and staging of malignant tumours. This study aimed to identify the static and dynamic features of 18F-FDG PET/CT in NUTM1-rearranged lung sarcomas. Case Description: A 46-year-old male patient underwent a chest CT scan for trauma, which revealed a tumor in the hilum of the left lung. The patient also underwent dynamic (chest) and static (whole body) PET/CT scans. The dynamic and static 18F-FDG PET/CT scans showed a tumor in the hilum of the left lung, with a size of 8.6×6.7 cm, an SUVmax of 17.6 and a Ki of 0.0668 ml/g/min. Final pathology and genetic testing confirmed NUTM1-rearranged lung sarcoma. Conclusions: This case shows dynamic and static 18F-FDG PET/CT and pathological features of NUTM1-rearranged lung sarcomas.
Keywords: NUTM1-rearranged lung sarcoma, 18F-FDG, PET/CT, dynamic, CT
Received: 10 Jul 2025; Accepted: 25 Aug 2025.
Copyright: © 2025 Wumener, Ye, Zhao, Zhang, E, Zhao and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xieraili Wumener, National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
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