CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Colorectal Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1668016
This article is part of the Research TopicAdvances in Proctology and Colorectal Surgery Volume IIView all 15 articles
laparoscopic right hemicolectomy in situs inversus totalis with cecal carcinoma:a case report and literature review
Provisionally accepted
- Second Department of Gastrointestinal Surgery, Hepatobiliary, Pancreatic and Intestinal Diseases Research Institute, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
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Background:Our patient exhibited situs inversus totalis (SIT) – a developmental quirk resulting in right-left transposition of all visceral organs, including the heart, liver, and spleen. While prior case reports have described colorectal carcinoma in individuals with SIT, to our knowledge, this case represents an exceptionally rare presentation of primary cecal carcinoma within this anatomical context. This case describes a patient undergoing laparoscopic right hemicolectomy for adenocarcinoma of the cecum. Case presentation: A patient presented to our institution in May 2024. Subsequent diagnostic workup confirmed a diagnosis of cecal carcinoma. Given the absolute contraindication for bowel preparation secondary to complete bowel obstruction, along with radiologically confirmed cecal malignancy and elevated serum tumor markers, a multidisciplinary consensus was reached to proceed with laparoscopic right hemicolectomy after obtaining proper informed consent from the patient's family.Pathology confirmed a T3N0M0 well-differentiated adenocarcinoma. Twelve-month consecutive postoperative follow-up data confirmed the absence of surgical complications such as anastomotic leakage or infection, as well as no clinical or radiographic evidence of disease recurrence. Conclusions:Although the reversed anatomy in SIT patients presents inherent technical challenges for laparoscopic surgery, this minimally invasive approach can still achieve comparable safety and efficacy to conventional procedures when performed by experienced surgeons with adequate anatomical understanding.
Keywords: Situs inversus totalis, colorectal cancer, Laparoscopic radical resection, case report, Tomography angiography
Received: 23 Jul 2025; Accepted: 09 Oct 2025.
Copyright: © 2025 Su, Zhong, Chen, Tian, Wu and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Bowen Su, subway0122@163.com
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