CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1670442
A case report of gastric serrated adenoma arising in a patient with bile reflux gastritis and related literature review
Provisionally accepted
- 1the Fifth Affiliated Hospital of Wenzhou Medical University and Lishui Central Hospital, Lishui, China
- 2Kanma Memorial Hospital, Tochigi, Japan
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Serrated adenoma is often found in the colorectum, but seldom found in stomach. We reported a case of a 70-year-old male with gastroscopy showed a elevated lesion with central depression on the gastric body, with clear margins. Background consistent with bile reflux gastritis. Endoscopic submucosal dissection (ESD) was performed. Histopathology confirmed a gastric serrated adenoma. This study reports the first documented case of gastric serrated adenoma arising in a background of bile reflux gastritis, suggesting bile reflux may be a potential risk factor for gastric serrated adenoma development.
Keywords: gastric, Serrated adenoma, Gastric serrated adenoma, Serrated lesions, Bile Reflux, gastric cancer
Received: 21 Jul 2025; Accepted: 22 Sep 2025.
Copyright: © 2025 Cai, Yan, Fu, Ye, Shao, Wang, Xu and Fu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lixia Fu, fulixials@163.com
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