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REVIEW article

Front. Oncol.

Sec. Surgical Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1672738

This article is part of the Research TopicArtificial Intelligence in Clinical Oncology: Enhancements in Tumor ManagementView all 10 articles

Advances in Artificial Intelligence for Precision Preoperative Assessment in Liver Surgery:A Comprehensive Review

Provisionally accepted
  • 1Department of General Surgery, Ningbo No 2 Hospital, Ningbo, China
  • 2School of Clinical Medicine, Hangzhou Medical College, Hangzhou, China
  • 3Department of Scientific Research, Ningbo No 2 Hospital, Ningbo, China

The final, formatted version of the article will be published soon.

The success rate of liver surgery is closely related to patients' individualized characteristics such as lesion benignity and malignancy, vascular variability, and liver function reserve, and the traditional assessment relies on surgeons' experience, which has the limitations of high subjectivity and low reproducibility. With the rapid development of artificial intelligence (AI) technology, especially the application of multimodal data fusion and deep learning, the goal of accurate decision-making and personalized medicine in liver surgery has been greatly promoted, facilitating the shift from empirical decision-making to accurate prediction of data. However, most of the current studies are small-sample, single-center data and there is no standardized liver imaging database, which is associated with data bias and overfitting of AI algorithms. In addition, the complexity of the liver structure and the dynamics of vascular variation greatly increase the difficulty of intraoperative monitoring. This paper systematically describes the key technologies and assessment areas of AI in preoperative assessment of liver surgery, focusing on the limitations of the current study and the future development direction, with the aim of providing a reference for the precise preoperative assessment of clinical AI, with a view to achieving better surgical results, improving the quality of postoperative recovery and the overall therapeutic effect of the patients.

Keywords: Artificial Intelligence1, liver surgery2, medical image analysis3, multimodal fusion4, machine learning5

Received: 24 Jul 2025; Accepted: 30 Sep 2025.

Copyright: © 2025 Qian, Haitao and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Shi-yi Qian, 1523694559@qq.com
Jiang Haitao, jht5019@aliyun.com

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