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CASE REPORT article

Front. Oncol.

Sec. Head and Neck Cancer

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1678310

Case Report: Free Fibula Flap for Post-Oncologic Mandibular Reconstruction, First Experience in Tirana

Provisionally accepted
Alice  Marzi ManfroniAlice Marzi Manfroni1*Marjon  SakoMarjon Sako2Nela  MatajNela Mataj2Deniada  ZhupaDeniada Zhupa3Francesco  LaganàFrancesco Laganà1
  • 1Maxillofacial Surgery Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
  • 2Maxillofacial Surgery Unit, University Hospital Center Mother Theresa, Tirana, Albania
  • 3Private Practice Maxillofacial Surgeon, Tirana, Albania

The final, formatted version of the article will be published soon.

Mandibular reconstruction using an osteocutaneous free fibular flap is a highly advanced microsurgical procedure, rarely performed in developing healthcare systems due to technical complexity and infrastructure demands. We present the first successful case performed in Tirana, Albania, demonstrating the feasibility of implementing such techniques in emerging surgical settings. A 54-year-old male diagnosed with squamous cell carcinoma of the left mandibular alveolar crest (cT4N1M0) underwent left hemimandibulectomy, bilateral neck dissection and immediate mandibular reconstruction using a right osteocutaneous fibular free flap. Preoperative Doppler ultrasonography confirmed sufficient vascular supply, excluding contraindications such as peripheral vascular disease and venous insufficiency. Fibula was harvested without tourniquet, improving vascular visualization and reducing ischemic time. A 4 × 7 cm skin paddle was included for intraoral soft tissue reconstruction. Cervical recipient vessels were isolated for microvascular anastomosis. Postoperative management involved intensive monitoring by a multidisciplinary team. Flap viability was assessed through color, temperature, capillary refill, and Doppler signals, with early mobilization and speech/swallowing therapy initiated promptly. The patient experienced an uneventful recovery with complete flap survival and functional restoration. This case highlights the potential to achieve complex microvascular reconstructions successfully in resource-limited environments through careful planning and interdisciplinary collaboration.

Keywords: Oral squamous cell carcinoma (OSCC), Fibula free flap, Mandibular reconstruciton, oncologic reconstruction, developing health care systems, Microsurgery

Received: 02 Aug 2025; Accepted: 05 Sep 2025.

Copyright: © 2025 Marzi Manfroni, Sako, Mataj, Zhupa and Laganà. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Alice Marzi Manfroni, Maxillofacial Surgery Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy

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