CASE REPORT article
Front. Oncol.
Sec. Gynecological Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1695646
This article is part of the Research TopicCutting-Edge Strategies in Screening, Prevention, and Treatment in Gynaecologic OncologyView all 36 articles
Giant spontaneous epidermal cyst of the labia minora: a rare case report and literature review
Provisionally accepted
- 1The Second Clinical Medical School, Henan University of Chinese Medicine, Zhengzhou, China
- 2Department of Gynaecology, Henan University of Chinese Medicine Henan Provincial Hospital of TCM, Zhengzhou, China
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Background: Epidermal cysts are benign subcutaneous masses resulting from the implantation of epithelial cells, following trauma or surgery. Giant spontaneous epidermal cysts of the labia minora are rare. To date, only 3 cases of epidermal cysts located in the labia minora have been reported worldwide. Case description: This study presents a case involving an epidermal cyst of the labia minora with a diameter exceeding 8 cm, accompanied by endometriosis within an episiotomy scar and a concurrent Bartholins's cyst. All lesions were surgically excised, successfully resolving the patient's symptoms, and the final pathological diagnosis confirmed an epidermal cyst and endometriosis. The patient recovered well postoperatively, and follow-up at 3 months revealed no discomfort or complications. Conclusion: This case shows that spontaneous epidermal cysts of the labia minora are very rare and can enlarge rapidly over a short period. Prompt and thorough surgical excision is recommended to prevent recurrence and the potential for malignant transformation.
Keywords: Epidermal Cyst, labia minora, Surgery, epidermal inclusion cyst, case report
Received: 30 Aug 2025; Accepted: 30 Sep 2025.
Copyright: © 2025 Li, Bai, Li, Li and Fu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ruili Li, reap1212@126.com
Jinying Fu, fujinying2003@163.com
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