CASE REPORT article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1699786
A Rare Cause of Duodenal Intussusception: The Pedunculated Brunner's gland hamartoma
Provisionally accepted- 1The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
- 2Hangzhou Normal University Affiliated Hospital, Hangzhou, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
BACKGROUND: Brunner’s gland hamartomas (BGHs) are primarily benign and typically do not exhibit characteristic clinical symptoms. The discovery and diagnosis of duodenal BGHs may require imaging assistance. Dissemination of this case can help inform future diagnosis and effective treatment. CASE SUMMARY: Herein, we report a case of a 43-year-old male presenting with bloating. The computed tomography (CT) found a strip-like, mixed-density lesion with fat attenuation in the duodenal canal, and the proximal intestine was dilated. Contrast-enhanced abdominal CT revealed the lesion had mild to moderate enhancement with incomplete intussusception. The lesion was resected entirely with the endoscope. Postoperative pathology confirmed a BGH. CONCLUSION: CT findings exhibit specific characteristics that are valuable for visualizing these lesions or their secondary manifestations. An elongated intraluminal mass lesion with heterogeneous density and fat attenuation may indicate a pedunculated duodenal Brunner’s gland hamartoma.
Keywords: Intestinal Polyps, Brunner's gland adenoma, Brunner's gland hamartoma, computed tomography, Endoscopic therapy
Received: 05 Sep 2025; Accepted: 26 Sep 2025.
Copyright: © 2025 Wang, Zhou, Huang, Zheng, Gu, Duan, Fan and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jian-Xia Xu, xjx129@163.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.