ORIGINAL RESEARCH article
Front. Oral Health
Sec. Oral Health Promotion
Volume 6 - 2025 | doi: 10.3389/froh.2025.1588737
This article is part of the Research TopicEnhancing Oral Health Literacy and Quality of Life: Strategies for a Healthier FutureView all 4 articles
Interdisciplinary research on periodontitis and depression: a bibliometric analysis of research trends, hotspots and future directions
Provisionally accepted
- 1Central South University, Changsha, China
- 2Lecong Hospital of Shunde Dental Centre, guangzhou, China
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Background: Periodontitis, a chronic inflammatory disease affecting nearly 50% of the global population, has been increasingly linked to depression, a prevalent psychiatric disorder. Methods: This study conducted a comprehensive bibliometric analysis to explore the association between periodontitis and depression, from 2000 to 2024 via the Web of Science Core Collection (WoSCC) database. Bibliometric parameters were extracted and bibliometric analysis was conducted via VOSviewer, and CiteSpace software. Results: A total of 205 publications, comprising 173 original articles and 32 reviews, were analyzed via VOSviewer and CiteSpace, with a focus on countries, institutions, authors, journals, keywords, and citations. The results revealed a significant increase in publications, with notable contributions from China, the USA, and Brazil, accounting for 43.9% of all studies. The collaborative networks highlight the growing interdisciplinary nature of this field. "Depression" (n = 71), "disease" (n = 66), "association" (n = 50), "oral health" (n = 47) and "stress" (n = 37) were the most frequent keywords, reflecting current research hotspots. Through the time map analysis of keyword clustering, we found that the research hotspots gradually changed from "risk factors", "chronic periodontitis" and "psychosocial factors" to "inflammation", "Alzheimer's disease" and "smoking" and other keywords. Keyword analyses identify emerging research hotspots, including the interplay of stress, anxiety, and inflammation.The number of related studies on periodontitis and depression continues to increase. The analysis of countries, authors and keywords reveals development trends, collaboration opportunities, and priority themes such as psychosocial factors and systemic inflammation. These findings provide a theoretical foundation for future research on periodontitis and depression.
Keywords: Periodontitis, Depression, Bibliometrics, VOSviewer, Citespace
Received: 06 Mar 2025; Accepted: 17 Jun 2025.
Copyright: © 2025 Tang, Xu, Zhang, Yuan and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dian Zhou, Central South University, Changsha, China
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