SYSTEMATIC REVIEW article
Front. Oral Health
Sec. Oral Cancers
Volume 6 - 2025 | doi: 10.3389/froh.2025.1601962
This article is part of the Research TopicEmerging Trends in Oral Cancer Research: A Focus on Molecular and Clinical AdvancesView all articles
Current perspectives and trend of ferroptosis in head and neck cancer: A bibliometric analysis
Provisionally accepted
- Anhui Medical University, Hefei, China
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Background: Ferroptosis, a form of regulated cell death driven by iron dependency, is also referred to as iron-mediated cell death. In recent years, ferroptosis has garnered considerable research interest as a distinct cell death mechanism, primarily characterized by excessive intracellular iron accumulation and the formation of lipid peroxides. Ferroptosis is intricately linked to the initiation and progression of a wide spectrum of diseases, notably cancers, neurodegenerative disordersincluding Alzheimer's and Parkinson's diseases-and cardiovascular conditions. Despite growing interest in ferroptosis within cancer research, systematic analyses and comprehensive visualizations of research hotspots, leading contributors, and emerging trends-particularly in the context of head and neck cancers-remain limited.This study conducted a bibliometric analysis using data retrieved from the
Keywords: ferroptosis, head and neck cancers, cancer therapy, cell apoptosis, bibliometric analysis
Received: 28 Mar 2025; Accepted: 29 Jul 2025.
Copyright: © 2025 Pan, Zhang, Zhao, Shao and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wei Shao, Anhui Medical University, Hefei, China
Xin Chen, Anhui Medical University, Hefei, China
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