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Front. Pharmacol., 21 December 2018
Sec. Predictive Toxicology

Corrigendum: The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats

\r\nQianying LiuQianying Liu1Zhixin LeiZhixin Lei2Qin WuQin Wu2Ihsan AwaisIhsan Awais2Muhammad A. B. ShabbirMuhammad A. B. Shabbir2Saeed AhmedSaeed Ahmed2Zainab FatimaZainab Fatima2Xu WangXu Wang2Yuanhu PanYuanhu Pan2Shuyu Xie*Shuyu Xie2*Zonghui Yuan,,*Zonghui Yuan1,2,3*
  • 1National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, China
  • 2MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, China
  • 3Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan, China

A Corrigendum on
The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats

by Liu, Q., Lei, Z., Wu, Q., Awais, I., Shabbir, M. A. B., Ahmed, S., et al. (2018). Front. Pharmacol. 9:870. doi: 10.3389/fphar.2018.00870

In the original article, there was a mistake in Figure 4 as published. Figure 4B was not displayed at the correct magnitude than that described in the figure legend. The corrected Figure 4 appears below.


Figure 4. Selected microphotographs of liver, kidney, adrenal gland, testis and uterus (200X and 400X). M275, 275 mg/kg diet. (A) Liver (200X), (B) kidney (200X), (C) adrenal (400X), (D) testis (200X), and (E) uterus (200X) of F0 and F1 from the control group; (a) Liver in the 275 mg/kg MEQ group (200X). The vacuoles with a large number of blood cells, and hyperplasia of the epithelioid cells of the bile duct were marked with arrows; (b) Kidney in the 275 mg/kg MEQ group (400X). The swelling and hyperplasia of renal vesicle wall cell, and degeneration and necrosis of renal tubular epithelium were marked with arrows; (c) Adrenal gland in the 275 mg/kg MEQ group (400X). The proliferation of fascicular zone cell, increased binuclear cell and adrenocortical tumor were marked with arrows; (d) Testis in the 275 mg/kg MEQ group (200X). The broadening of interstitial, necrosis and dissolution of spermatogonial cells and spermatocytes in the lumen were marked with arrows; (e) Uterus in the 275 mg/kg MEQ group (200X). The incomplete structure and neutrophil infiltration in submucosal glands were marked with arrows.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: reproductive toxicity, teratogenicity, mequindox, Wistar rats, developmental toxicity

Citation: Liu Q, Lei Z, Wu Q, Awais I, Shabbir MAB, Ahmed S, Fatima Z, Wang X, Pan Y, Xie S and Yuan Z (2018) Corrigendum: The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats. Front. Pharmacol. 9:1489. doi: 10.3389/fphar.2018.01489

Received: 28 October 2018; Accepted: 05 December 2018;
Published: 21 December 2018.

Edited and reviewed by: Eleonore Fröhlich, Medical University of Graz, Austria

Copyright © 2018 Liu, Lei, Wu, Awais, Shabbir, Ahmed, Fatima, Wang, Pan, Xie and Yuan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Shuyu Xie,
Zonghui Yuan,

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