SYSTEMATIC REVIEW article
Front. Pharmacol.
Sec. Pharmacoepidemiology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1545870
This article is part of the Research TopicPharmacoepidemiology in Chronic DiseasesView all 13 articles
Bibliometric and Visual Analysis of Traditional Chinese Medicine Flavonoids in the Treatment of Obesity from 2004 to 2024
Provisionally accepted
- 1The Third People's Hospital of Hainan Province, Sanya, China
- 2Guilin Medical University, Guilin, Guangxi Zhuang Region, China
- 3The First People’s Hospital of Yulin, Yulin, Shaanxi Province, China
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Objective: Flavonoids show promise in treating obesity, but their role in traditional Chinese medicine (TCM) lacks systematic quantitative analysis. This study explores research trends and hotspots of TCM flavonoids in obesity treatment from 2004 to 2024. Methods: Publications were retrieved from the Web of Science database. Bibliometric and visual analyses were performed using R, VOSviewer, and CiteSpace.Results: A total of 1,563 articles were analyzed. Publications steadily increased, with a notable surge from 2018 to 2022. China led in output and international collaboration, with key partners including the Egypt Knowledge Base. The Journal of Agricultural and Food Chemistry was most cited, while the Journal of Ethnopharmacology published the most articles. Frequent keywords included "antioxidants," "diabetes," "polyphenols," "oxidative stress," and "inflammation." Network pharmacology and metabolomics emerged as dominant methods. Common flavonoids studied were anthocyanins, quercetin, catechins, and proanthocyanidins. Antioxidant, antiinflammatory, and enzyme-inhibitory mechanisms were major research focuses.TCM flavonoids are gaining attention in obesity research. This analysis identifies current hotspots and provides direction for future studies.
Keywords: Flavonoids, Obesity, Bibliometric, Traditional Chinese Medicine, Antioxidants, anti-inflammatory
Received: 16 Dec 2024; Accepted: 27 Jun 2025.
Copyright: © 2025 Yan, Wu, Zhang, Li, Liu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yuanyuan Yan, The Third People's Hospital of Hainan Province, Sanya, China
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