ORIGINAL RESEARCH article
Front. Pharmacol.
Sec. Drugs Outcomes Research and Policies
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1576442
PPRS Improves Prescription Safety, Efficiency, and Cost-Effectiveness in Pediatric Outpatients: A Western China Study
Provisionally accepted
- Children‘s Hospital of Chongqing Medical University, Chongqing, China
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Objective: The study's objective is to investigate the prescription rationality rate, time efficiency, and estimated economic benefits of a preprescription review system (PPRS) in pediatric outpatients in a five-year retrospective study in western China Method: This retrospective before-after study compared data from two phases: pre-intervention phase (2019: PPRS not yet implemented), and post-intervention phase (2020-2023: PPRS fully operational). The study evaluated three key endpoints: primary endpoint was the prescription rationality rate; the secondary endpoints were time efficiency (interval from prescription to drug dispensing) and suggested economic benefits (estimated benefit-cost ratio). Descriptive analyses were conducted to investigate the prescription rationality rate before and after PPRS implementation. The time interval from prescription to drug dispensing was analyzed from 2019 to 2023 using one-way ANOVA. Suggested economic benefit was evaluated under the healthcare system perspective with estimated benefit-cost ratio. Results: The PPRS implementation was correlated with an increase in the
Keywords: 2, 3, pre-prescription review system, time efficiency, economic, pharmacist, pediatric
Received: 14 Feb 2025; Accepted: 01 Jul 2025.
Copyright: © 2025 Yang, He, Li, Wang and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ling Xiu Wang, Children‘s Hospital of Chongqing Medical University, Chongqing, China
Lin Song, Children‘s Hospital of Chongqing Medical University, Chongqing, China
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