CASE REPORT article
Front. Pharmacol.
Sec. Predictive Toxicology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1610147
Aortic dissection induced by licorice tablets overdose: a case report
Provisionally accepted
- 1Tianjin Medical University General Hospital, Tianjin, China
- 2Tianjin Normal University, Tianjin, China
- 3Tianjin Third Central Hospital, Tianjin, China
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Objective: To investigate the pathogenesis of aortic dissection induced by licorice tablet poisoning.Methods: A case of aortic dissection caused by poisoning by overtaking licorice tablets was reported. The patient's medical history, laboratory examination, imaging results, and treatment process were analyzed, and the relevant literature was reviewed.Results: This case suggests that licorice poisoning is a potential risk factor for aortic dissection, which needs to be paid attention to in clinical practice. In the face of acute poisoning, in addition to paying attention to the conventional treatment measures of acute poisoning, we should pay more attention to the pharmacological mechanism of drugs and their induced complications to avoid subjective judgment and reduce misdiagnosis and abuse.
Keywords: Liquorice, Glycyrrhizic Acid, aortic dissection, Poisoning, pseudohyperaldosteronism
Received: 11 Apr 2025; Accepted: 19 Aug 2025.
Copyright: © 2025 Luo, Wang, Liu, Zhang, CHAI and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lijun Wang, Tianjin Medical University General Hospital, Tianjin, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.