ORIGINAL RESEARCH article
Front. Pharmacol.
Sec. Pharmacology of Infectious Diseases
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1621090
The Role of Probiotic Supplementation in Reducing Helicobacter pylori Recurrence After Classic Quadruple Therapy
Provisionally accepted
- 1Jinxi People's Hospital of Kunshan, (Kunshan Elderly Hospital ), Kunshan, China
- 2Kunshan Traditional Chinese Medicine Hospital, Kunshan, China
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Helicobacter pylori (H. pylori) infection remains a global public health issue, closely linked to peptic ulcer disease, gastric cancer, and MALT lymphoma. Although classic bismuth-containing quadruple therapy achieves high eradication rates, recurrence after treatment is still a significant concern. Recent evidence suggests that probiotics may support gastrointestinal homeostasis, modulate immune responses, and help prevent H. pylori reinfection. This study aimed to evaluate whether probiotic supplementation reduces H. pylori recurrence following classic quadruple therapy.
Keywords: Helicobacter pylori, Probiotic supplementation, Quadruple therapy, Recurrence, Gut Microbiota
Received: 30 Apr 2025; Accepted: 20 Jun 2025.
Copyright: © 2025 Zhao, Chen, Wang, Xia and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wei Yang, Kunshan Traditional Chinese Medicine Hospital, Kunshan, China
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