MINI REVIEW article
Front. Pharmacol.
Sec. Ethnopharmacology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1623476
Research Progress of Dissolving Microneedles in the Field of Component Administration of Traditional Chinese Medicine
Provisionally accepted
- 1Shandong First Medical University, Jinan, China
- 2Shandong First Medical University, Tai'an, China
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focuses on the applications of traditional Chinese medicine (TCM) delivered through microneedles. It elaborates on how microneedle technology overcomes the limitations of conventional TCM administration methods, such as oral, transdermal, and injectable routes, which are often associated with low bioavailability, difficulties in dosage control, and poor patient compliance. The manuscript provides a detailed account of the preparation process of TCM-extractloaded dissolving microneedles. Furthermore, it presents the effects of these DMNs in areas such as skin repair, anti-inflammation, lipid reduction, and weight loss. In addition, it explores the potential applications of TCM microneedle-based combination therapies in cancer treatment. Through systematically integrating existing studies on TCM microneedles, the manuscript not only elaborates on the technical principles and innovative advantages of microneedle-based TCM delivery but also summarizes the pharmacological mechanisms and clinical translation potential of this technology from multiple dimensions. This precise alignment with the research hotspot of integrating TCM modernization with modern pharmaceutical technologies provides a comprehensive knowledge framework and research insights for the field of TCM microneedles, highly consistent with the journal's goal of advancing pharmacological progress.
Keywords: Dissolving MNs, Traditional Chinese Medicine, Transdermal administration, MNs preparation, skin restoration, Analgesia and anti-inflammation
Received: 07 May 2025; Accepted: 04 Aug 2025.
Copyright: © 2025 Yang, Zhang, Niu, Wang, Liu, Zhu and Meng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Pengju Zhu, Shandong First Medical University, Tai'an, China
Fanda Meng, Shandong First Medical University, Jinan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.