REVIEW article
Front. Pharmacol.
Sec. Ethnopharmacology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1631637
This article is part of the Research TopicReviews in Ethnopharmacology: 2025View all 27 articles
Recent advances in polysaccharides derived from the Dendrobium nobile Lindl.: preparation strategies, structural characteristics, biological activity, and structure-activity relationships
Provisionally accepted
- Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
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Dendrobium nobile Lindl. (D. nobile) has significant medicinal value. D. nobile is used in traditional Chinese medicine and is widely popular as a functional food and health supplement due to its nourishing properties and high safety. Among its key bioactive constituents, polysaccharides exhibit promising applications across medicine, personal care, food, and agriculture, owing to their anti-photoaging, improvement of complications of diabetes mellitus, ovarian protective, gastric protective, neuroprotective, anti-inflammatory and anti-viral effects. Despite these multifaceted benefits, research on D. nobile polysaccharides remains limited relative to more extensively studied components such as alkaloids and flavonoids. This review systematically summarizes current advances in extraction techniques, structural features, bioactivities, and structure-activity relationships of D. nobile polysaccharides, providing a theoretical framework for their future medical development and application.
Keywords: Dendrobium nobile Lindl., Polysaccharides, extraction, purification, Structural characteristics, Biological activity
Received: 20 May 2025; Accepted: 07 Jul 2025.
Copyright: © 2025 Zhou, Bi, Zhang, Wang, Zhang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Meng Wang, Heilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang Province, China
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