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ORIGINAL RESEARCH article

Front. Pharmacol.

Sec. Drugs Outcomes Research and Policies

Volume 16 - 2025 | doi: 10.3389/fphar.2025.1648571

This article is part of the Research TopicPerspectives and Opinions in Health Services, Volume IIView all 17 articles

Investigation and Analysis on the Charging Status and Standard of Pharmacy Intravenous Admixture Service in China

Provisionally accepted
Jie  CaoJie Cao*Shu  ZhouShu ZhouJie  LiJie LiDan  WangDan WangYongning  LuYongning LuXue-Feng  CaiXue-Feng Cai*
  • Dept. of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

The final, formatted version of the article will be published soon.

Objective: The charging policy of pharmacy intravenous admixture services (PIVAS) is not merely a minor "billing issue" confined to individual hospitals, but rather a critical component that impacts the safety, efficiency, equity, and long-term sustainability of the national healthcare system. To establish a foundation for the national charging standard of PIVAS, this study comprehensively investigated and analyzed the operational costs and current charging policies of PIVAS across 30 provinces in China. Methods: Questionnaires were distributed through the "Wenjuan Xing" platform from May 6th to July 1st, 2022. After data generation and export by the platform, statistical and descriptive analyses of the questionnaire results were conducted using statistical software, including EXCEL, SPSS. Results: A total of 761 PIVAS surveyed, 91.59% were affiliated with the pharmacy department, while 6.70% belonged to the hospital independent department. Most PIVAS strongly agreed with imposing fees, while most tertiary hospitals agreed that dispensing fees should be categorized based on hospital levels; however, most secondary hospitals disagreed. Approximately 60.58% of PIVAS have implemented a charging system which allows charges after inspection and evaluation. Regarding changes for different drugs nationwide, common drugs had an average charge standard of 4.39 yuan per bag while antibacterial drugs averaged 5.01 yuan per bag. Hazardous drugs had an average charge of 23.17 yuan per bag, whereas parenteral nutrition solutions averaged 38.75 yuan per bag. The annual operating cost of PIVAS in China was approximately RMB 2,098,100, with the integrated operating cost comprising 89.36% of the total, while dispensing cost accounted for only 10.64%. Human costs emerged as the highest annual consumption(74.20%), followed by facility maintenance (4.77%) . Conclusion: The lack of a unified inspection and evaluation standard as well as charging standard in China is currently an urgent issue that needs to be addressed. The existing charging standard falls below the recommended level, thus it is necessary to develop a more reasonable and equitable charging standard that takes into account operational costs. This study can serve as an empirical reference for national medical insurance and health administration authorities in establishing unified regulatory standards and dynamic pricing adjustment mechanisms for PIVAS.

Keywords: Pharmacy intravenous admixture service, current charging policy, charging standard, charging status, China

Received: 17 Jun 2025; Accepted: 30 Sep 2025.

Copyright: © 2025 Cao, Zhou, Li, Wang, Lu and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Jie Cao, whxh_caojie@163.com
Xue-Feng Cai, yjkcai@163.com

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