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SYSTEMATIC REVIEW article

Front. Pharmacol.

Sec. Ethnopharmacology

Volume 16 - 2025 | doi: 10.3389/fphar.2025.1661803

This article is part of the Research TopicEnhancing Cancer Therapy: Integrating Plant-Derived Bioactives with Chemotherapy through Traditional Knowledge and Modern AdvancesView all 23 articles

8 Specific Chinese herbal injections combined with chemotherapy for breast cancer: A systematic review and network meta-analysis of comparative safety and efficacy

Provisionally accepted
运泽  史运泽 史Jianhao  ChengJianhao ChengYichen  ZhaoYichen ZhaoLong  HeLong HeLifeng  DuanLifeng DuanHuichao  WangHuichao WangXiaoyang  HuXiaoyang Hu*
  • 黑龙江中医药大学, 黑龙江省哈尔滨市, China

The final, formatted version of the article will be published soon.

Background: Breast cancer(BC)poses a major threat to human health. Since the beginning of the 21st century, numerous clinical studies conducted in China have reported the therapeutic advantages of combining Chinese herbal injections (CHIs) with chemotherapy; however, comparative evaluations of different CHIs remain scarce. This multidimensional network meta-analysis was designed to compare the efficacy of various CHIs and to identify the optimal combination regimen of CHI plus chemotherapy for breast cancer treatment.

Keywords: Chinese herbal injection, breast cancer, chemotherapy, Network meta-analysis, Systematic evaluation

Received: 08 Jul 2025; Accepted: 08 Sep 2025.

Copyright: © 2025 史, Cheng, Zhao, He, Duan, Wang and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xiaoyang Hu, 黑龙江中医药大学, 黑龙江省哈尔滨市, China

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