REVIEW article
Front. Pharmacol.
Sec. Ethnopharmacology
Volume 16 - 2025 | doi: 10.3389/fphar.2025.1673075
Research on the Mechanisms of Plant Bioactive Metabolites in Anti-Skin Aging and Future Development Prospects
Provisionally accepted
- Changchun University of Chinese Medicine, Changchun, China
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With the accelerated pace of modern life and the influence of various environmental factors, skin aging has become a widespread health and aesthetic concern worldwide. Therefore, there is an urgent need for safe, effective and cost-efficient options for the prevention and treatment of skin aging. Researchers have been actively exploring anti-skin aging metabolites that can replace synthetic chemical agents. In recent years, natural plant bioactive metabolites isolated from plants have been considered as good alternatives and have been favored by an increasing number of researchers due to their rich content of bioactive metabolites and low side effects. Botanical bioactive metabolites have become a focal point in the field of anti-aging skincare due to their effectiveness in alleviating visible signs of skin aging and their potential to enhance the overall health of the skin. we collected relevant literature published between 2010 and 2025 using keywords such as 'skin aging', 'plant bioactive metabolites', 'antioxidant', 'reactive oxygen species', 'matrix metalloproteinases', 'inflammation', and others. This review describes skin aging, common plant (e.g., rice, ginseng, tea, etc.) bioactive metabolites and their efficacy and mechanism of action in delaying skin aging. In addition, the development potential and future trends of botanical bioactive metabolites are explored with the aim of providing a more holistic approach to skin aging care and offering valuable insights into the use of botanical bioactive metabolites as important metabolites in the formulation of anti-aging products.
Keywords: Skin Aging, Plant Bioactive metabolites, antioxidant, Inflammation, Reactive oxygen species(ROS)
Received: 29 Jul 2025; Accepted: 25 Sep 2025.
Copyright: © 2025 Haoran, Jinyv, Shikui and Jingwei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Cao Shikui, csk1968@126.com
Lv Jingwei, jingwei-lv@hotmail.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.