Frontiers in Pharmacology

Original Research

Published on 02 May 2024

Multidrug resistance transporters P-gp and BCRP limit the efficacy of ATR inhibitor ceralasertib in cancer cells

in Pharmacology of Anti-Cancer Drugs

Xuan-Yu Chen
Zhuo-Xun Wu
Jing-Quan Wang
Qiu-Xu Teng
Hailin Tang
Qianwen Liu
Zhe-Sheng Chen
Wenkuan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1400699

3,167 views
6 citations

Original Research

Published on 02 May 2024

The influence of the way of regression on the results obtained by the receptorial responsiveness method (RRM), a procedure to estimate a change in the concentration of a pharmacological agonist near the receptor

in Experimental Pharmacology and Drug Discovery

Ignac Ovari
Gabor Viczjan
Tamas Erdei
Barbara Takacs
Vera Tarjanyi
Judit Zsuga
Miklos Szucs
Zoltan Szilvassy
Bela Juhasz
Rudolf Gesztelyi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1375955

1,146 views

Original Research

Published on 02 May 2024

Population pharmacokinetics of intravenous daptomycin in critically ill patients: implications for selection of dosage regimens

in Drug Metabolism and Transport

Jianhua Wu
Xiangyi Zheng
Liu Zhang
Jiajun Wang
Yifei Lv
Yujie Xi
Dongfang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1378872

2,579 views
1 citation

Original Research

Published on 02 May 2024

The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7

in Pharmacology of Ion Channels and Channelopathies

Fan Zhao
Yuanyuan Liu
Yiyu Liu
Qi Ye
Hongtao Yang
Mingze Gui
Yongbo Song

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1374183

1,875 views

Original Research

Published on 02 May 2024

Deciphering the functional role of clinical mutations in ABCB1, ABCC1, and ABCG2 ABC transporters in endometrial cancer

in Experimental Pharmacology and Drug Discovery

Aayushi Gupta
Manu Smriti Singh
Bipin Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1380371

3,588 views
2 citations

Brief Research Report

Published on 02 May 2024

A real-world experience of venetoclax combined with hypomethylating agents vs. monotherapy hypomethylating agents in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia patients

in Drugs Outcomes Research and Policies

Ludan Zhang
Rui Ge
Deng Pan
Pengjie Yue
Jingwen Zhang
Renjie Bian
Xiaojing Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1265840

2,607 views
1 citation

Original Research

Published on 02 May 2024

Exosomes derived from HUVECs alleviate ischemia-reperfusion induced inflammation in neural cells by upregulating KLF14 expression

in Neuropharmacology

Jianxin Qin
Lihong Zhou
Lei Yu
Jingwen Ye
Feng Wang
Jin Zhou
Yunjuan Gu
Gang Chen
Xia Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1365928

3,303 views
6 citations

Original Research

Published on 02 May 2024

Cacao consumption improves passive avoidance memory impairment in a rat model of Alzheimer’s disease: the role of hippocampal synaptic plasticity and oxidative stress

in Ethnopharmacology

Hamid Shokati Basir
Naser Mirazi
Alireza Komaki
Abdolkarim Hosseini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1379264

4,298 views
9 citations

Original Research

Published on 02 May 2024

The association between ondansetron use and mortality risk of traumatic brain injury patients: a population-based study

in Experimental Pharmacology and Drug Discovery

Ruoran Wang
Jing Zhang
Jianguo Xu
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1362309

3,781 views
2 citations

Original Research

Published on 02 May 2024

Gastric cancer actionable genomic alterations across diverse populations worldwide and pharmacogenomics strategies based on precision oncology

in Pharmacogenetics and Pharmacogenomics

Gabriela Echeverría-Garcés
María José Ramos-Medina
Rodrigo Vargas
Alejandro Cabrera-Andrade
Adriana Altamirano-Colina
María Paula Freire
Juliana Montalvo-Guerrero
Sebastián Rivera-Orellana
Paulina Echeverría-Espinoza
Luis A. Quiñones

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1373007

4,934 views
6 citations

Original Research

Published on 02 May 2024

Physiologically based pharmacokinetic modeling to predict the pharmacokinetics of codeine in different CYP2D6 phenotypes

in Drug Metabolism and Transport

Yujie Yang
Xiqian Zhang
Yirong Wang
Heng Xi
Min Xu
Liang Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1342515

4,626 views
2 citations

Original Research

Published on 01 May 2024

Phytic acid attenuates acetaminophen-induced hepatotoxicity via modulating iron-mediated oxidative stress and SIRT-1 expression in mice

in Gastrointestinal and Hepatic Pharmacology

Hend M. Hassan
Nehal H. M. Abdel-Halim
Ibrahim El-Shenbaby
Manar A. Helmy
Maha O. Hammad
Ola A. Habotta
Eman M. El Nashar
Mansour A. Alghamdi
Rashid A. Aldahhan
Khulood M. Al-Khater

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1384834

2,785 views
4 citations

Systematic Review

Published on 01 May 2024

The effect of bupivacaine on analgesia and safety in patients undergoing hemorrhoidectomy: a meta-analysis

in Drugs Outcomes Research and Policies

Haixia Lu
Min Cai
Dongxi Zhou
Weiwei Li
Hanzhong Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1331965

3,264 views
1 citation

Review

Published on 01 May 2024

Natural products’ antiangiogenic roles in gynecological cancer

in Ethnopharmacology

Shangmei Jia
Ling Li
Chenghao Yu
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353056

3,318 views
5 citations

Case Report

Published on 01 May 2024

Case report: Successful anesthesia management of noncardiac surgery in a patient with single atrium

in Cardiovascular and Smooth Muscle Pharmacology

Hong Cao
Mengmeng Jiang
Zhao Zhuang
Shoushi Wang
Qianqian Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370263

2,185 views
1 citation

Original Research

Published on 01 May 2024

Exploring the link between pyrethroids exposure and dopaminergic degeneration through morphometric, immunofluorescence, and in-silico approaches: the therapeutic role of chitosan-encapsulated curcumin nanoparticles

in Neuropharmacology

Badriyah S. Alotaibi
Amany Abdel-Rahman Mohamed
Yasmina M. Abd-Elhakim
Ahmed E. Noreldin
Moustafa Elhamouly
Tarek Khamis
Ali H. El-Far
Manal E. Alosaimi
Naief Dahran
Leena S. Alqahtani

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388784

3,387 views
7 citations