Frontiers in Pharmacology

Original Research

Published on 06 Jan 2023

Comprehensive analysis of hypoxia-related genes for prognosis value, immune status, and therapy in osteosarcoma patients

in Pharmacology of Anti-Cancer Drugs

Tao Han
Zhouwei Wu
Zhe Zhang
Jinghao Liang
Chuanpeng Xia
Hede Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1088732

2,758 views
6 citations

Original Research

Published on 06 Jan 2023

Enhanced secretion of hepatocyte growth factor in human umbilical cord mesenchymal stem cells ameliorates pulmonary fibrosis induced by bleomycin in rats

in Respiratory Pharmacology

Huanjie Chen
Yulong Luo
Yiping Zhu
Yongshun Ye
Difei Chen
Xinyu Song
Zhulin Xiao
Ming Liu
Shiyue Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1070736

3,111 views
12 citations

Original Research

Published on 06 Jan 2023

Functional evaluation of cyclosporine metabolism by CYP3A4 variants and potential drug interactions

in Drug Metabolism and Transport

Qihui Kong
Nanyong Gao
Yahui Wang
Guoxin Hu
Jianchang Qian
Bingbing Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044817

3,748 views
5 citations

Original Research

Published on 06 Jan 2023

Tetramethylpyrazine ameliorates acute lung injury by regulating the Rac1/LIMK1 signaling pathway

in Respiratory Pharmacology

Simin Min
Weiting Tao
Dushan Ding
Xiaonan Zhang
Shidi Zhao
Yong Zhang
Xiaojie Liu
Kefei Gao
Saisai Liu
Li Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1005014

4,162 views
14 citations

Review

Published on 06 Jan 2023

Extracellular vesicles derived from host and gut microbiota as promising nanocarriers for targeted therapy in osteoporosis and osteoarthritis

in Integrative and Regenerative Pharmacology

Kenneth Chat Pan Cheung
Ma Jiao
Chen Xingxuan
Jia Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1051134

6,953 views
12 citations

Editorial

Published on 06 Jan 2023

Editorial: Novel biomarkers for anticancer therapy

in Pharmacology of Anti-Cancer Drugs

Ting Wang
Zhe-Sheng Chen
Chen Shi
Liang Ouyang
Hongtao Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1109761

1,897 views

Original Research

Published on 06 Jan 2023

Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

in Pharmacology of Anti-Cancer Drugs

Yan Wang
Di Qin
Yiyao Gao
Yunxin Zhang
Yao Liu
Lihong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1098800

6,480 views
7 citations

Original Research

Published on 06 Jan 2023

Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease

in Renal Pharmacology

Yiyun Song
Hui Yu
Qiaoling Sun
Fei Pei
Qing Xia
Zhaoli Gao
Xianhua Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1035755

4,353 views
9 citations

Original Research

Published on 06 Jan 2023

Gender-specific association between the regular use of statins and the risk of irritable bowel syndrome: A population-based prospective cohort study

in Pharmacoepidemiology

Xiaoying Zhang
Yuyao Liu
Yanghui Ou
Man Yang
Jinqiu Yuan
Qiangsheng He
Yanfei Li
Ningning Mi
Peng Xie
Wenjing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044542

6,733 views
2 citations

Original Research

Published on 06 Jan 2023

Phosphatidyl Inositol 3-Kinase (PI3K)-Inhibitor CDZ173 protects against LPS-induced osteolysis

in Experimental Pharmacology and Drug Discovery

Zuoxing Wu
Xuedong Li
Xiaohui Chen
Xuemei He
Yu Chen
Long Zhang
Zan Li
Mengyu Yang
Guixin Yuan
Baohong Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1021714

4,093 views
2 citations

Case Report

Published on 06 Jan 2023

BRAF L485–P490 deletion mutant metastatic melanoma sensitive to BRAF and MEK inhibition: A case report and literature review

in Pharmacology of Anti-Cancer Drugs

Simeng Zhang
Zichang Yang
Yu Cheng
Xiaoyu Guo
Chang Liu
Shuo Wang
Lingyun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1019217

2,086 views
5 citations

Study Protocol

Published on 06 Jan 2023

Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial

in Ethnopharmacology

Rui Fang
Hua Hu
Yue Zhou
Shanshan Wang
Zhigang Mei
Ruining She
Xiwen Peng
Qiling Jiang
Xiangyuan Wang
Le Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2022.967457

5,844 views
4 citations

Original Research

Published on 06 Jan 2023

Systematic analysis of the role and significance of target genes of active ingredients of traditional Chinese medicine injections in the progression and immune microenvironment of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Chao Wang
Lili Yang
Shaoheng Xu
Hui Guo
Hewen Guan
Qiannan Wang
Xueyan Jiang
Mingyang Fei
Jinbao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1095965

2,553 views
3 citations

Original Research

Published on 06 Jan 2023

Expanding the toolbox of metabolically stable lipid prodrug strategies

in Experimental Pharmacology and Drug Discovery

Kiran S. Toti
Nicole Pribut
Michael D’Erasmo
Madhuri Dasari
Savita K. Sharma
Perry W. Bartsch
Samantha L. Burton
Hannah B. Gold
Anatoliy Bushnev
Cynthia A. Derdeyn

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1083284

3,484 views
5 citations

Original Research

Published on 06 Jan 2023

Identification of ferroptosis, necroptosis, and pyroptosis-associated genes in periodontitis-affected human periodontal tissue using integrated bioinformatic analysis

in Inflammation Pharmacology

Shuaifei Pan
Yue Li
Haokun He
Shuguang Cheng
Jiang Li
Janak L. Pathak

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1098851

14,000 views
28 citations

Review

Published on 06 Jan 2023

Hypothermia combined with neuroprotective adjuvants shortens the duration of hospitalization in infants with hypoxic ischemic encephalopathy: Meta-analysis

in Translational Pharmacology

Andrea Ovcjak
Riley Pontello
Steve P. Miller
Hong-Shuo Sun
Zhong-Ping Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1037131

3,956 views
10 citations