Frontiers in Pharmacology

Original Research

Published on 09 Apr 2025

TRPC3 contributes to cyclophosphamide-induced cystitis progression by enhancing bladder fibrosis through activation of the TGF-β/smad pathway

in Renal Pharmacology

Ruixiang Luo
Wenshuang Li
Junlong Huang
Zheng Liu
Chi Zhang
Honglu Ding
Jialiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565156

980 views

Original Research

Published on 09 Apr 2025

Umbilical cord stem cells therapy against bacterial pneumonia based on zebrafish pneumonia model

in Inflammation Pharmacology

Xueli Chen
Jian Jin
Xia Chen
Yabin Wu
Youjun Guo
Zuoyu Qian
Hui Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546193

734 views

Review

Published on 09 Apr 2025

Role of Achyranthes aspera in neurodegenerative diseases: current evidence and future directions

in Neuropharmacology

Huaiqing Luo
Siwen Wei
Shujun Fu
Li Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1511011

969 views

Original Research

Published on 09 Apr 2025

HPLC-UV method development and validation for anticancer drug sorafenib and the co-prescribed drug dexamethasone: application to pharmacokinetic evaluation of sorafenib nanoformulations

in Translational Pharmacology

Abdul Mateen
Abad Khan
Ismail Khan
Saifullah Khan Khalil
Lateef Ahmad
Muhammad Junaid
Saqib Jehan
Muhammad Sohail Anwar
Muhammad Faheem
Abdul Salam

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1442762

943 views

Original Research

Published on 09 Apr 2025

Danggui Shaoyao San ameliorates Alzheimer’s disease by regulating lipid metabolism and inhibiting neuronal ferroptosis through the AMPK/Sp1/ACSL4 signaling pathway

in Experimental Pharmacology and Drug Discovery

Kai Gong
Shuang Zhou
Li Xiao
Mengzhen Xu
Yuhe Zhou
Kaihui Lu
Xin Yu
Jiang Zhu
Chuanguo Liu
Qingjun Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588375

1,136 views

Original Research

Published on 09 Apr 2025

Impacts of sulfate polysaccharide JCS1S2 on retinal neovascularization in oxygen-induced retinopathy rats

in Experimental Pharmacology and Drug Discovery

Yang Bai
Rui Wang
Can Jin
Lili Wang
Yun Tang
Han Wang
Kan Ding
Shanjun Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499420

728 views

Original Research

Published on 09 Apr 2025

Therapeutic effects and mechanisms of Xinmaitong formula for type 2 diabetes mellitus via GLP-1R signaling

in Ethnopharmacology

Weidong Pu
Yang Pan
Kang Yang
Jian Gao
Fen Tian
Jingrui Song
Yubing Huang
Yanmei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575450

1,043 views

Original Research

Published on 09 Apr 2025

Microfluidic chip-based co-culture system for modeling human joint inflammation in osteoarthritis research

in Integrative and Regenerative Pharmacology

Hosein Mirazi
Scott T. Wood

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579228

1,171 views

Review

Published on 09 Apr 2025

Aster tataricus L. f.: a review on the botany, phytochemistry, ethnopharmacology, pharmacology, toxicology and comprehensive utilization

in Ethnopharmacology

Xinyi Zhang
Meiqi Liu
Xiaozhuang Zhang
Lengleng Ma
Shiyi Song
Meitong Pan
Shumin Huang
Weichao Ren
Wei Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581505

989 views

Review

Published on 09 Apr 2025

Regulation of pyroptosis by natural products in ulcerative colitis: mechanisms and therapeutic potential

in Experimental Pharmacology and Drug Discovery

Xiaobei Lu
Yapeng Sun
Zhaoyi Zhang
Zhigang Sun
Shaohui Wang
Erping Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573684

1,292 views

Original Research

Published on 09 Apr 2025

The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Huizhen Ye
Xiwen Wu
Gehao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515552

953 views

Case Report

Published on 09 Apr 2025

Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab

in Neuropharmacology

Raquel Piñar-Morales
Raquel Calle-Calle
Maria Carrasco-Garcia
Cristina Davila-Arias
Luisa Maria Villar-Guimerans
Francisco J. Barrero Hernandez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571699

906 views

Original Research

Published on 09 Apr 2025

Discovery of CMNPD31124 as a novel marine-derived PKMYT1 inhibitor for pancreatic ductal adenocarcinoma therapy: computational and biological insights

in Experimental Pharmacology and Drug Discovery

Chaojie Huang
Ting Wang
Rui Chen
Yunyun Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569765

891 views

Review

Published on 09 Apr 2025

Ginseng and its functional components in non-alcoholic fatty liver disease: therapeutic effects and multi-target pharmacological mechanisms

in Ethnopharmacology

Ping Xiao
Zhaorui Ye
Xiuyan Li
Quansheng Feng
Yue Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540255

1,273 views

Original Research

Published on 09 Apr 2025

Population pharmacokinetics and dose optimization of voriconazole in patients with COVID-19-associated pulmonary aspergillosis

in Pharmacology of Infectious Diseases

Hui Wang
Yue Shen
Xuemei Luo
Lu Jin
Huaijun Zhu
Jing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554370

768 views

Review

Published on 09 Apr 2025

The roles of extracellular vesicles in mental disorders: information carriers, biomarkers, therapeutic agents

in Neuropharmacology

Longkun Wang
Ruixue Liu
Ying Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1591469

744 views