Frontiers in Pharmacology

Perspective

Published on 25 Feb 2025

Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores

in Gastrointestinal and Hepatic Pharmacology

Jaehee V. Shim
Markus Rehberg
Britta Wagenhuber
Piet H. van der Graaf
Douglas W. Chung

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1479666

3,699 views

Original Research

Published on 25 Feb 2025

Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma

in Experimental Pharmacology and Drug Discovery

Nana Wang
Shuming Cao
Xiaofeng Tan
Meirong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540636

1,651 views

Original Research

Published on 25 Feb 2025

Fenvalerate exposure induces AKT/AMPK-dependent alterations in glucose metabolism in hepatoma cells

in Pharmacology of Anti-Cancer Drugs

Lu Sun
Zheng-Guo Cui
Qianwen Feng
Jibran Sualeh Muhammad
Yu-Jie Jin
Songji Zhao
Lingqi Zhou
Cheng-AI Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540567

1,967 views

Opinion

Published on 25 Feb 2025

The inherent defects of cold atmospheric plasma for the treatment of burns

in Integrative and Regenerative Pharmacology

Yingying Li
Hong Guan
Guojuan Fan
Jinlong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540704

1,093 views

Original Research

Published on 25 Feb 2025

Aspirin-triggered DHA metabolites inhibit angiogenesis

in Inflammation Pharmacology

M. Vara-Messler
L. Trevisi
E. Zulato
G. E. Ramaschi
P. Risé
C. Pinna
S. Indraccolo
A. Sala
C. Bolego

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524980

1,906 views

Review

Published on 25 Feb 2025

MLKL as an emerging machinery for modulating organelle dynamics: regulatory mechanisms, pathophysiological significance, and targeted therapeutics

in Inflammation Pharmacology

Yang Wang
Wei Wei
Yu Zhang
Jingrong Miao
Xiaofeng Bao
Chunfeng Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512968

3,482 views
2 citations

Review

Published on 25 Feb 2025

Exploring manzamine a: a promising anti-lung cancer agent from marine sponge Haliclona sp

in Experimental Pharmacology and Drug Discovery

Min Su
Jie Zhu
Luyuan Bai
Yu Cao
Shaohui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525210

2,243 views
13 citations

Original Research

Published on 25 Feb 2025

Pharmacokinetics and pharmacodynamics of insulin lispro 25 versus the original preparation (Humalog®25) in Chinese healthy male volunteers

in Drug Metabolism and Transport

Mingxue Zhu
Yuan Chen
Lei Wan
Zhongping Li
Junliang Pu
Chengyong Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533548

1,844 views

Original Research

Published on 25 Feb 2025

Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma

in Experimental Pharmacology and Drug Discovery

Zhaoguang Song
Wenyan Yu
Xuqing Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545913

1,206 views

Original Research

Published on 25 Feb 2025

Community pharmacy professionals’ knowledge, attitudes, and practices toward substandard and falsified medicines and associated factors in Bahir Dar City, Northwest Ethiopia

in Drugs Outcomes Research and Policies

Biset Asrade Mekonnen
Kidest Berhanu
Nebiyu Solomon
Minichil Chanie Worku
Yeniewa Kerie Anagaw

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523709

2,275 views
1 citation

Original Research

Published on 25 Feb 2025

Exploring the potential anti-senescence effects of soybean-derived peptide Soymetide in mice hippocampal neurons via the Wnt/β-catenin pathway

in Neuropharmacology

Asmita Garg
Jyotshana Saroj
Saurabh Tiwari
Uttara Das
Neetu Shukla
Jimut Kanti Ghosh
Sanghamitra Bandyopadhyay

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510337

2,685 views

Original Research

Published on 25 Feb 2025

Time-varying cost-effectiveness analysis of sodium-glucose cotransporter-2 inhibitors in Chinese patients with heart failure and reduced ejection fraction: A microsimulation of the real-world population

in Drugs Outcomes Research and Policies

Xinyu Zou
Xingchen He
Qingyang Shi
Si Wang
Nan Li
Yiling Zhou
Ming Hu
Li Luo
Yiwen Shen
Ye Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527972

2,127 views
2 citations

Original Research

Published on 25 Feb 2025

Neuroprotective effects of ethanol extraction from Rubia yunnanensis Diels on chronic cerebral hypoperfusion: modulation of the System Xc-/GSH/GPX4 axis to alleviate oxidative stress and ferroptosis

in Neuropharmacology

Jianghao Cheng
Xiaoxia Ma
Jie Tao
Xiaoli Jiang
Pu Chen
Xiaohua Duan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552228

2,069 views

Original Research

Published on 25 Feb 2025

Targeting TRPV1 channels in desensitized neural afferent pathways may help mitigate pain and lower urinary tract symptoms caused by prostatitis

in Experimental Pharmacology and Drug Discovery

ZhiPeng Jiang
AnGuo Li
Wen Luo
XiKe Luo
DeCan Liang
Jing Li
KaiHua Tang
Lei Liu
ZongMin Long
Ruiyu Miao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541684

1,831 views
1 citation

Mini Review

Published on 25 Feb 2025

Preparation, structural characterization, bioactivities, and potential clinical applications of the polysaccharides from Paris polyphylla: a review

in Ethnopharmacology

Ailong Sha
Yuanyuan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539237

1,385 views
1 citation

Original Research

Published on 25 Feb 2025

Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights

in Experimental Pharmacology and Drug Discovery

Waad A. Samman
Esraa M. Mosalam
Dalia S. Saif
Mahmoud S. Abdallah
Abdel-Aziz A. Zidan
Amany Said Sallam
Shimaa Abdelsattar
Fatma Omar Khalil
Amany E. Elashkar
Somia Mokabel Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507693

1,560 views
2 citations