Frontiers in Pharmacology

Original Research

Published on 29 Jan 2024

Population pharmacokinetics and individualized dosing of tigecycline for critically ill patients: a prospective study with intensive sampling

in Experimental Pharmacology and Drug Discovery

Wei Su
Shuping Song
Jieqiong Liu
Haitao Yu
Binbin Feng
Yinshan Wu
Feng Guo
Zhenwei Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1342947

2,397 views
2 citations

Original Research

Published on 29 Jan 2024

Real world drug treatment models for pregnancy complicated with urinary tract infection in China from 2018 to 2022: a cross-section analysis

in Drugs Outcomes Research and Policies

Jing Jin
Changyan Li
Yuqing He
Jiaqian Pan
JiaLei Zhu
Jing Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1349121

3,225 views
2 citations

Original Research

Published on 29 Jan 2024

Traditional Chinese medicine Zhusha Anshen Wan: protective effects on liver, kidney, and intestine of the individual drugs using 1H NMR metabolomics

in Ethnopharmacology

Dalu Wang
Chong Yu
Beixing Liu
Haifeng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353325

2,898 views
2 citations

Original Research

Published on 29 Jan 2024

Impact of a pharmacist-led educational intervention on knowledge, attitude, and practice toward the rational use of antibiotics among healthcare workers in a secondary care hospital in Punjab, Pakistan

in Drugs Outcomes Research and Policies

Shairyar Afzal
Farman Ullah Khan
Muhammad Tahir Aqeel
Matti Ullah
Mishal Bajwa
Masoom Akhtar
Muhammad Majid

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1327576

3,904 views
11 citations

Original Research

Published on 29 Jan 2024

Aloe-emodin exhibits growth-suppressive effects on androgen-independent human prostate cancer DU145 cells via inhibiting the Wnt/β-catenin signaling pathway: an in vitro and in silico study

in Experimental Pharmacology and Drug Discovery

Talib Hussain
Ahmed Alafnan
Ibrahim Abdullah Almazni
Nawal Helmi
Afrasim Moin
Hanadi M. Baeissa
Amir Mahgoub Awadelkareem
AbdElmoneim O. Elkhalifa
Tahani Bakhsh
Abdulrahman Alzahrani

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1325184

2,934 views
8 citations

Original Research

Published on 29 Jan 2024

Mechanisms underlying the therapeutic effects of cinobufagin in treating melanoma based on network pharmacology, single-cell RNA sequencing data, molecular docking, and molecular dynamics simulation

in Pharmacology of Anti-Cancer Drugs

Jiansheng Yang
Chunchao Cheng
Zhuolin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1315965

6,519 views
3 citations

Systematic Review

Published on 29 Jan 2024

The dynamic equilibrium between the protective and toxic effects of matrine in the development of liver injury: a systematic review and meta-analysis

in Ethnopharmacology

Weiyi Feng
Te-chan Kao
Jiajie Jiang
Xinyu Zeng
Shuang Chen
Jinhao Zeng
Yu Chen
Xiao Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1315584

3,303 views
3 citations

Review

Published on 29 Jan 2024

Natural products for the treatment of chemotherapy-related cognitive impairment and prospects of nose-to-brain drug delivery

in Ethnopharmacology

Yu-Qiong He
Can-Can Zhou
Sheng-Gui Jiang
Wen-Qian Lan
Feng Zhang
Xia Tao
Wan-Sheng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1292807

4,047 views
2 citations

Original Research

Published on 29 Jan 2024

Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics and in silico electrophysiological models

in Ethnopharmacology

Muqeet Wahid
Fatima Saqib
Ghulam Abbas
Shahid Shah
Abdulrahman Alshammari
Thamer H. Albekairi
Anam Ali
Muhammad Khurm
Mohammad S. Mubarak

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1277594

3,547 views

Original Research

Published on 29 Jan 2024

Ethics of access to newly approved expensive medical treatments: multi-stakeholder dialogues in a publicly funded healthcare system

in Drugs Outcomes Research and Policies

Charlotte H. C. Bomhof
Jilles Smids
Sybren Sybesma
Maartje Schermer
Eline M. Bunnik

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1265029

3,043 views
1 citation

Original Research

Published on 29 Jan 2024

An integrated in vitro approach on the enzymatic and antioxidant mechanisms of four commercially available essential oils (Copaifera officinalis, Gaultheria fragrantissima, Helichrysum italicum, and Syzygium aromaticum) traditionally used topically for their anti-inflammatory effects

in Ethnopharmacology

Pilar Cebollada
Nelson G. M. Gomes
Paula B. Andrade
Víctor López

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1310439

3,561 views
6 citations

Clinical Trial

Published on 26 Jan 2024

Pharmacokinetics, pharmacodynamics and safety of 15 mg-tolvaptan administered orally for 7 consecutive days to Chinese patients with child-Pugh B cirrhosis

in Drug Metabolism and Transport

Hongzhong Liu
Yongfeng Wang
Tao Liu
Yingxuan Chen
Xin Zheng
Ming Liu
Qian Zhao
Minde Zeng
Ji Jiang
Yimin Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1324299

2,406 views

Review

Published on 26 Jan 2024

From antimicrobial to anticancer: unraveling the potential of pleurocidin and pleurocidin-derived peptides in the treatment of cancers

in Experimental Pharmacology and Drug Discovery

Ewelina Piktel
Urszula Wnorowska
Joanna Gorbacz-Konończuk
Jakub Sienkiewicz
Katarzyna Głuszek
Sławomir Okła
Robert Bucki

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1340029

3,500 views
6 citations

Case Report

Published on 26 Jan 2024

Case report: One case of refractory membranous nephropathy with hypokalemia after rituximab infusion was switched to obinutuzumab without recurrence of hypokalemia

in Predictive Toxicology

Yao Zhang
Jing Sun
Jie Gao
Weiyan Sun
Liang Xu
Chunjuan Zhai
WenYan Su
Haiping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1347880

2,526 views
9 citations

Original Research

Published on 26 Jan 2024

Exploration of biomarkers for efficacy evaluation of traditional Chinese medicine syndromes of acute exacerbation of chronic obstructive pulmonary disease based on metabolomics

in Drug Metabolism and Transport

Zhang Hailong
Si Yimei
Du Yan
Liu Xinguang
Li Jiansheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1302950

3,910 views
4 citations

Original Research

Published on 26 Jan 2024

Novel in vitro evidence on the beneficial effect of quercetin treatment in vascular calcification

in Ethnopharmacology

E. Ceccherini
I. Gisone
E. Persiani
C. Ippolito
A. Falleni
A. Cecchettini
F. Vozzi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1330374

2,918 views
12 citations