Frontiers in Pharmacology | Drug Metabolism and Transport

Review

Published on 24 Jan 2025

Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects

in Drug Metabolism and Transport

Dwi Pratiwi Kasmara
Erlina Abdullah
Zaliha Harun
Fatmi Nirmala Sari
Norhashima Abd Rashid
Seong Lin Teoh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522814

1,710 views

Original Research

Published on 22 Jan 2025

Characterizing the plasma protein binding profiles of chemistry diversified antisense oligonucleotides in human and mouse plasma using an ultrafiltration method

in Drug Metabolism and Transport

Cassandra Yun
Kazuki Fukami
Raku Shinkyo
Rongrong (Rosa) Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481937

1,625 views
1 citation

Original Research

Published on 17 Jan 2025

Comparative study on the bioavailability and bioequivalence of rifapentine capsules in humans

in Drug Metabolism and Transport

Ying Qi
Pengfei Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1463575

1,391 views

Original Research

Published on 15 Jan 2025

Pharmacokinetics of 7,8-dihydroxyflavone in neonatal mice with hypoxia-ischemia related brain injury

in Drug Metabolism and Transport

Sin Yin Lim
Cameron O. Scarlett
Sefer Yapici
Peter Ferrazzano
Pelin Cengiz

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508696

1,169 views

Original Research

Published on 13 Jan 2025

Effect of ultrasound combined with microbubbles therapy on tumor hypoxic microenvironment

in Drug Metabolism and Transport

Yuyi Feng
Danxia Qiu
Yangcheng He
Hai Jin
Liping Chen
Fen Xi
Zhiwen Hu
Yanlin Xie
Yucai Li
Minhua Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1502349

900 views

Original Research

Published on 13 Jan 2025

Effects of acteoside from Cistanche tubulosa on the plasma metabolome of cancer-related fatigue mice inoculated with colon cancer cells

in Drug Metabolism and Transport

Shilei Zhang
Fukai Gong
Jiali Liu
Shuping You
Tao Liu
Jianhua Yang
Junping Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370264

1,775 views
1 citation

Original Research

Published on 10 Jan 2025

Amphotericin B tissue penetration and pharmacokinetics in healthy and Candida albicans-infected rats: insights from microdialysis and population modeling

in Drug Metabolism and Transport

Valdeene Vieira Santos
Laiz Campos Pereira
Jackeline Marley Santos de Araújo
Matheus Antônio da Hora Borges
Carolina Magalhães Brandão
Luisa Oliveira Santos
Cristiane Flora Villarreal
Francine Johansson Azeredo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515462

893 views

Original Research

Published on 09 Jan 2025

UGT2B15 single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans

in Drug Metabolism and Transport

Jin-Woo Park
Jong-Min Kim
Young Yoon Bang
Kyoung-Ah Kim
Sungwook Yu
Ji-Young Park

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1507915

857 views

Original Research

Published on 08 Jan 2025

The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist

in Drug Metabolism and Transport

Xiaoting Gu
Xiaohe Li
Weixue Tian
Chaoyue Zheng
Yutian Cai
Xiang Xu
Conglu Zhao
Hongting Liu
Yao Sun
Zhilin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1510903

976 views

Original Research

Published on 08 Jan 2025

stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments

in Drug Metabolism and Transport

Roberto Visintainer
Anna Fochesato
Daniele Boaretti
Stefano Giampiccolo
Shayne Watson
Micha Levi
Federico Reali
Luca Marchetti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462193

825 views

Original Research

Published on 07 Jan 2025

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia

in Drug Metabolism and Transport

Mihaela Butiulca
Lenard Farczadi
Silvia Imre
Camil Eugen Vari
Laurian Vlase
Bogdan Cordos
Leonard Azamfirei
Alexandra Elena Lazar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494646

809 views

Original Research

Published on 07 Jan 2025

The effects of clinical and pharmacological factors on the ratio of clozapine to norclozapine in psychiatric patients

in Drug Metabolism and Transport

Anna Mach
Anna Wnorowska
Marcin Siwek
Marcin Wojnar
Maria Radziwoń-Zaleska

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1518739

914 views

Methods

Published on 06 Jan 2025

Liquid chromatography-tandem mass spectrometry for the quantification of ripretinib and its metabolites DP-5439 in human plasma

in Drug Metabolism and Transport

Jiahui Lin
Aiting Jiang
Juntao Zheng
Jingjing Wu
Hao Li
Shirong Cai
Yulong He
Xiao Chen
Guoping Zhong
Ke-Jing Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506931

850 views
1 citation

Original Research

Published on 03 Jan 2025

Ceftriaxone-associated dysbiosis decreases voriconazole bioavailability by upregulating intestinal P-glycoprotein expression through activation of the Nrf2-mediated signalling pathway

in Drug Metabolism and Transport

Xiaokang Wang
Chunxiao Ye
Xixiao Yang
Maoxun Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1522271

815 views

Original Research

Published on 03 Jan 2025

Bioequivalence study of fluticasone propionate nebuliser suspensions in healthy Chinese subjects

in Drug Metabolism and Transport

Feng Cheng
Tao Shen
Fucheng Zhang
Chenghao Lei
Ye Zhu
GuoJun Luo
Dawei Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452596

1,335 views

Clinical Trial

Published on 03 Jan 2025

Evaluating the pharmacokinetics and safety of blonanserin tablets and Lonasen®: a randomized, open-label, two-period, two-sequence, self-crossover phase I clinical trial

in Drug Metabolism and Transport

Bo Qiu
Haojing Song
Xue Sun
Congyang Ding
Runxuan Du
Wanjun Bai
Zhanjun Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1511214

844 views