Frontiers in Pharmacology | Drug Metabolism and Transport

Original Research

Published on 19 Apr 2024

Investigation of the hypoglycemic mechanism of the ShenQi compound formula through metabonomics and 16S rRNA sequencing

in Drug Metabolism and Transport

Juan Gao
Xiujuan Zhou
Hong Gao
Guiping Xu
Chunguang Xie
Hongyan Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1349244

2,181 views
2 citations

Original Research

Published on 09 Apr 2024

Iodine-induced synthetic method and pharmacokinetic study of cis- and trans-crocetin

in Drug Metabolism and Transport

Boshen Li
Yuxuan Zhang
Zhiqiang Yang
Xiaolin Li
Jun Yang
Kai Luo
Renjie Wang
Chengrong Xiao
Maoxing Li
Yue Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1364286

1,479 views
1 citation

Original Research

Published on 08 Apr 2024

Effect of P. corylifolia on the pharmacokinetic profile of tofacitinib and the underlying mechanism

in Drug Metabolism and Transport

Yu Wang
Quan Zhou
Huihui Wang
Wei Song
Jianfeng Wang
Abdullah Al Mamun
Peiwu Geng
Yunfang Zhou
Shuanghu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1351882

1,632 views
2 citations

Clinical Trial

Published on 04 Apr 2024

Assessment of omeprazole and famotidine effects on the pharmacokinetics of tacrolimus in patients following kidney transplant–randomized controlled trial

in Drug Metabolism and Transport

Miłosz Miedziaszczyk
Marek Karczewski
Tomasz Grabowski
Anna Wolc
Ilona Idasiak-Piechocka

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352323

3,302 views
5 citations

Original Research

Published on 02 Apr 2024

Pharmacokinetics of desflurane uptake and disposition in piglets

in Drug Metabolism and Transport

Chih-Cherng Lu
Shung-Tai Ho
Oliver Yao-Pu Hu
Cheng-Huei Hsiong
Yuan-Chen Cheng
Che-Hao Hsu
Tso-Chou Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1339690

3,786 views

Original Research

Published on 27 Mar 2024

Clinical and pharmacological factors influencing serum clozapine and norclozapine levels

in Drug Metabolism and Transport

Anna Mach
Anna Wnorowska
Marcin Siwek
Marcin Wojnar
Maria Radziwoń-Zaleska

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1356813

2,567 views
2 citations

Original Research

Published on 25 Mar 2024

Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice

in Drug Metabolism and Transport

Heechun Kwak
Min-Soo Kim
Suyong Kim
Jiyoung Kim
Yasunori Aoki
Suk-Jae Chung
Hyun-Ja Nam
Wooin Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352842

2,253 views
1 citation

Original Research

Published on 18 Mar 2024

Application of machine learning combined with population pharmacokinetics to improve individual prediction of vancomycin clearance in simulated adult patients

in Drug Metabolism and Transport

Guodong Li
Yubo Sun
Liping Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352113

2,158 views
3 citations

Mini Review

Published on 13 Mar 2024

Emerging therapeutic drug monitoring technologies: considerations and opportunities in precision medicine

in Drug Metabolism and Transport

Winnie S. Liang
Brett Beaulieu-Jones
Susan Smalley
Michael Snyder
Laura H. Goetz
Nicholas J. Schork

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348112

7,397 views
10 citations

Original Research

Published on 11 Mar 2024

Establishment of a pharmacokinetics and pharmacodynamics model of Schisandra lignans against hippocampal neurotransmitters in AD rats based on microdi-alysis liquid chromatography-mass spectrometry

in Drug Metabolism and Transport

Jinpeng Zhang
Xinyuan Cui
Shuo Zhao
Zenghui Chang
Junshuo Zhang
Yufeng Chen
Jiale Liu
Guohao Sun
Yiyuan Wang
Yuanyuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1342121

1,955 views
2 citations

Original Research

Published on 11 Mar 2024

Potential pharmacological mechanisms of tanshinone IIA in the treatment of human neuroblastoma based on network pharmacological and molecular docking Technology

in Drug Metabolism and Transport

Ning Tang
Yan Wang
Jiarui Miao
Yang Zhao
Yue Cao
Wentao Sun
Jingke Zhang
Hua Sui
Bing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363415

3,521 views
4 citations

Original Research

Published on 04 Mar 2024

Population pharmacokinetic model for oral ORIN1001 in Chinese patients with advanced solid tumors

in Drug Metabolism and Transport

Xiaoqing Li
Yunhai Bo
Qingping Zeng
Lei Diao
Stephanie Greene
John Patterson
Lu Liu
Fen Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1322557

2,113 views
6 citations

Original Research

Published on 04 Mar 2024

Exploring inter-ethnic and inter-patient variability and optimal dosing of osimertinib: a physiologically based pharmacokinetic modeling approach

in Drug Metabolism and Transport

Feng Liang
Yimei Zhang
Qian Xue
Na Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363259

1,797 views
2 citations

Original Research

Published on 01 Mar 2024

Optimization and preparation of a compound cod liver oil film former agent: an orthogonal design

in Drug Metabolism and Transport

Yao He
Ying Zhang
Zheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1296448

1,957 views
2 citations

Review

Published on 20 Feb 2024

A journey into the regulatory secrets of the de novo purine nucleotide biosynthesis

in Drug Metabolism and Transport

Nour Ayoub
Antoine Gedeon
Hélène Munier-Lehmann

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1329011

7,320 views
6 citations

Original Research

Published on 20 Feb 2024

Ivacaftor pharmacokinetics and lymphatic transport after enteral administration in rats

in Drug Metabolism and Transport

Jiří Pozniak
Pavel Ryšánek
David Smrčka
Petr Kozlík
Tomáš Křížek
Jaroslava Šmardová
Anežka Nováková
Debanjan Das
Daniel Bobek
Mahak Arora

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1331637

2,539 views
3 citations