Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 16 May 2025

TLR4 as a therapeutic target: Antidepressant mechanism of saikosaponin A in regulating the NF-κB/BDNF axis and mitigating oxidative stress and inflammation in vivo and in vitro

in Ethnopharmacology

Lin Tan
Jiayue Li
Dingcheng Sun
Xinyi Tian
Xiaoli Zhong
Yiyi Shan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1585290

690 views

Systematic Review

Published on 16 May 2025

Effects of cryptotanshinone in treatment of polycystic ovary syndrome in rats: a systematic review and meta-analysis

in Ethnopharmacology

Pingping Su
Xv Wang
Ruoqian Cai
Chang Yan
Yun Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561164

715 views

Original Research

Published on 16 May 2025

Cold- and hot-classified botanical drugs differentially modulate gut microbiota: linking TCM emic classification to microbial ecology

in Ethnopharmacology

Huan Yang
Chenyi Shao
Zhihao Liu
Xiaoyu Zhang
Yinhui Liu
Jing Xiao
Li Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545619

630 views

Review

Published on 16 May 2025

Biological effects of cinnamaldehyde in animal cancer models: a systematic review and meta-analysis

in Ethnopharmacology

Dan Luo
Xu Luo
Jinghui Xie
Keying Ye
Xiangjin Wang
Xiyue Hu
Chenhao Liu
Yi Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557088

761 views

Review

Accepted on 15 May 2025

Efficacy and safety of oral Chinese medicine combined with chemotherapy: A Systematic Review and Network Meta-analysis

in Ethnopharmacology

Ma Yuqi
Li Jia
Shen Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579613

191 views

Original Research

Published on 15 May 2025

Ginger (Zingiber officinale) dietary supplementation in mice regulates liver antioxidant defense systems in a dose- and age-dependent

in Ethnopharmacology

Maima Matin
Kamil Wysocki
Jarosław Olav Horbańczuk
Luciana Rossi
Atanas G. Atanasov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597599

648 views

Original Research

Published on 15 May 2025

Neuroprotective effects of astaxanthin in a scopolamine-induced rat model of Alzheimer’s disease through antioxidant/anti-inflammatory pathways and opioid/benzodiazepine receptors: attenuation of Nrf2, NF-κB, and interconnected pathways

in Ethnopharmacology

Zeinab Rastinpour
Sajad Fakhri
Fatemeh Abbaszadeh
Mohammad Ranjbari
Amir Kiani
Mohammed Namiq Amin
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589751

922 views

Original Research

Published on 15 May 2025

Effect of the total flavonoids of Dracocephalum moldavica L. on metabolic associated fatty liver disease in rats

in Ethnopharmacology

Xiaoyu Sun
Na Ge
Qingqing Liang
Qian Wang
Hui Yu
Min Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549515

661 views

Original Research

Published on 15 May 2025

Hochuekkito accelerates recovery from cisplatin induced-muscle atrophy accompanied by slow-twitch fiber-specific microRNA upregulation in mice

in Ethnopharmacology

Hitomi Sekine
Chinami Matsumoto
Naoki Fujitsuka
Sachiko Mogami
Shunsuke Ohnishi
Hiroshi Takeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1502563

485 views

Systematic Review

Published on 15 May 2025

From ‘traditional’ remedies to ‘modern’ supplements: a systematic review and meta-analysis of pharmaceutical adulteration in weight-loss natural products

in Ethnopharmacology

Dang Thuc Anh Phan
Chuenjid Kongkaew
Michael Heinrich
Thi Cam Minh Dao
Thi Ha Vo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594975

1,124 views

Original Research

Published on 15 May 2025

Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target

in Ethnopharmacology

Wu Di
Li Minghan
Huang Zining
Zhou Chunshi
Hu Xiangyu
Wang Zidong
Wu Gang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512631

692 views

Original Research

Published on 15 May 2025

Herbal and alternative medicine use: a cross sectional study to evaluate the prevalence and predictors of use in cancer patients

in Ethnopharmacology

Mahmoud Al-Masri
Rula Darwish
Yasmin Safi
Aseel Mustafa
Dina Alzyoud
Mohammad Almasri
Bilal Kahhaleh
Mohammad Khader

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535795

525 views

Systematic Review

Published on 14 May 2025

Shoutai pills for treating recurrent miscarriage: a systematic review and meta-analysis of the safety and clinical efficacy in 11 randomized controlled trials

in Ethnopharmacology

Lijun Ruan
Ying Cai
Yuan Yin
Fang Liu
Minyi Li
Guangming Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540073

540 views

Systematic Review

Published on 14 May 2025

Cytotoxic effect of different Uncaria tomentosa (cat’s claw) extracts, fractions on normal and cancer cells: a systematic review

in Ethnopharmacology

Adriana A. Lopes
Juliana da Silva Coppede
Pedro de Pádua G. Amatto
Davi Casale Aragon
Suzelei de Castro França
Fabio Carmona
Ana Maria S. Pereira

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584840

738 views

Original Research

Published on 14 May 2025

Salidroside can protect against ferroptosis in cardiomyocytes and may be related to the regulation of GGT1

in Ethnopharmacology

Tianhang Feng
Jing Shi
Jinghua Zhao
Qin Zhao
Tao Wang
Sha Wan
Chen Fan
Sijia Wang
Chunyou Lai
Yutong Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580506

733 views

Original Research

Accepted on 13 May 2025

Metabolic Profiling and Antimicrobial Activity of Bistorta amplexicaulis D. Don by invitro Implicated Through Computational Studies

in Ethnopharmacology

Hanan Javid
Umar Yousuf
Roof Ul Qadir
Junaid Magray
Bilal Ahmad Wani
Tajamul Islam
Prof Irshad A Nawchoo
Shabana Gulzar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575727

223 views