Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Original Research

Published on 16 May 2023

Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway

in Gastrointestinal and Hepatic Pharmacology

Doha Reda
Gehad E. Elshopakey
Talat A. Albukhari
Samah J. Almehmadi
Bassem Refaat
Engy F. Risha
Hebatallah A. Mahgoub
Mohamed E. El-Boshy
Fatma M. Abdelhamid

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1164512

8,430 views
25 citations

Original Research

Published on 15 May 2023

Comprehensive transcriptomic analysis and meta-analysis identify therapeutic effects of N-acetylcysteine in nonalcoholic fatty liver disease

in Gastrointestinal and Hepatic Pharmacology

Keungmo Yang
Hee-Hoon Kim
Young-Ri Shim
Tom Ryu
Chang Wook Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1186582

3,576 views
4 citations

Review

Published on 15 May 2023

Ferroptosis as an emerging therapeutic target in liver diseases

in Gastrointestinal and Hepatic Pharmacology

Yuzhen Lu
Junjie Hu
Liang Chen
Shan Li
Ming Yuan
Xianxiang Tian
Peng Cao
Zhenpeng Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1196287

6,860 views
13 citations

Original Research

Published on 12 May 2023

Therapeutic effect of fenofibrate for non-alcoholic steatohepatitis in mouse models is dependent on regime design

in Gastrointestinal and Hepatic Pharmacology

Xinxue Wang
Jia Luo
Zhuoheng Lu
Shenzhe Fang
Mengxia Sun
Wenjing Luo
Jianwei Shen
Aiming Liu
Hua Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1190458

3,947 views
3 citations

Review

Published on 11 May 2023

The effect of ginsenosides on liver injury in preclinical studies: a systematic review and meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Xing-Bo Bian
Peng-Cheng Yu
Xiao-Hang Yang
Liu Han
Qi-Yao Wang
Li Zhang
Lian-Xue Zhang
Xin Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1184774

3,192 views
8 citations

Review

Published on 11 May 2023

Gallbladder cancer: current and future treatment options

in Gastrointestinal and Hepatic Pharmacology

Yanzhao Zhou
Kun Yuan
Yi Yang
Zemin Ji
Dezheng Zhou
Jingzhong Ouyang
Zhengzheng Wang
Fuqiang Wang
Chang Liu
Qingjun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1183619

23,472 views
41 citations

Original Research

Published on 09 May 2023

Uncovering key molecules and immune landscape in cholestatic liver injury: implications for pathogenesis and drug therapy

in Gastrointestinal and Hepatic Pharmacology

Shuailing Song
Xiao Li
Chong Geng
Yaoyu Guo
Yi Yang
Chunhui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1171512

4,128 views
3 citations

Mini Review

Published on 05 May 2023

Targeting ferroptosis, a novel programmed cell death, for the potential of alcohol-related liver disease therapy

in Gastrointestinal and Hepatic Pharmacology

Jing-Fen Shi
Yu’e Liu
Yan Wang
Ru Gao
Yi Wang
Jun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1194343

4,562 views
15 citations

Review

Published on 05 May 2023

Personalized treatment for hepatocellular carcinoma in the era of targeted medicine and bioengineering

in Gastrointestinal and Hepatic Pharmacology

Hang Sun
Huayu Yang
Yilei Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1150151

6,880 views
17 citations

Systematic Review

Published on 02 May 2023

Global research progress of visceral hypersensitivity and irritable bowel syndrome: bibliometrics and visualized analysis

in Gastrointestinal and Hepatic Pharmacology

Siyu Tian
Hang Zhang
Siqi Chen
Pengning Wu
Min Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1175057

8,464 views
13 citations

Editorial

Published on 27 Apr 2023

Editorial: Emerging mechanistic insights of selective and Nonselective Autophagy in liver and gut diseases and their treatment strategies in the era of COVID-19

in Gastrointestinal and Hepatic Pharmacology

Md. Abdul Alim Al-Bari
Manoj B. Menon
Nabil Eid

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1206291

1,129 views

Original Research

Published on 25 Apr 2023

Artemisitene Alters LPS-Induced Oxidative stress, inflammation and Ferroptosis in Liver Through Nrf2/HO-1 and NF-kB Pathway

in Gastrointestinal and Hepatic Pharmacology

Changzhi Zhao
Congshu Xiao
Songqiao Feng
Jianxin Bai

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1177542

6,673 views
39 citations

Original Research

Published on 21 Apr 2023

Potential prognostic and immunotherapeutic value of calponin 1: A pan-cancer analysis

in Gastrointestinal and Hepatic Pharmacology

Hengli Zhou
Junyu Ke
Changhua Liu
Menglu Zhu
Bijuan Xiao
Qi Wang
Rui Hou
Yueer Zheng
Yongqiang Wu
Xingting Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1184250

4,160 views
4 citations

Original Research

Published on 18 Apr 2023

Effect of remimazolam tosilate on the incidence of hypoxemia in elderly patients undergoing gastrointestinal endoscopy: A bi-center, prospective, randomized controlled study

in Gastrointestinal and Hepatic Pharmacology

Fang Liu
Xiaoyan Cheng
Yingjie Wang
Kai Li
Tianliang Peng
Ningning Fang
Kalyan K. Pasunooti
Seungho Jun
Xiaomei Yang
Jianbo Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1131391

5,080 views
20 citations

Clinical Trial

Published on 07 Apr 2023

Effects of oleoylethanolamide supplementation on inflammatory biomarkers, oxidative stress and antioxidant parameters of obese patients with NAFLD on a calorie-restricted diet: A randomized controlled trial

in Gastrointestinal and Hepatic Pharmacology

Helda Tutunchi
Farideh Zolrahim
Mahlagha Nikbaf-Shandiz
Fatemeh Naeini
Alireza Ostadrahimi
Sina Naghshi
Reza Salek
Farzad Najafipour

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1144550

4,509 views
10 citations

Clinical Trial

Published on 06 Apr 2023

Impact of glucagon-like peptide 1 receptor agonist liraglutide and dipeptidyl peptidase-4 inhibitor sitagliptin on bowel cleaning and gastrointestinal symptoms in type 2 diabetes

in Gastrointestinal and Hepatic Pharmacology

Yan Tong
Jian Qing Huang
Yang Chen
Mei Tu
Wei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1176206

4,300 views
14 citations