Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Original Research

Published on 14 Apr 2025

Mirabegron induces selective changes in the faecal microbiota of HFHFr rats without altering bile acid composition

in Gastrointestinal and Hepatic Pharmacology

Roger Bentanachs
Lluïsa Miró
Patricia Ramírez-Carrasco
Rosa M. Sánchez
Manuel Bernabeu
Concepció Amat
Marta Alegret
Anna Pérez-Bosque
Núria Roglans
Juan C. Laguna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547749

1,208 views

Review

Published on 08 Apr 2025

Endogenous micropeptides as potential diagnostic biomarkers and therapeutic drugs

in Gastrointestinal and Hepatic Pharmacology

Aixi Zhong
Shuai Li
Jingxuan Zhang
Jingyuan Zhao
Chenhui Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545575

754 views

Review

Published on 07 Apr 2025

Dual signaling pathways of TGF-β superfamily cytokines in hepatocytes: balancing liver homeostasis and disease progression

in Gastrointestinal and Hepatic Pharmacology

Roohi Chaudhary
Ralf Weiskirchen
Marcelo Ehrlich
Yoav I. Henis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580500

2,327 views

Original Research

Published on 07 Apr 2025

Alteration of salivary Streptococcus is associated with statin therapy in older adults: a cohort study

in Gastrointestinal and Hepatic Pharmacology

Daisuke Hisamatsu
Yusuke Ogata
Wataru Suda
Yo Mabuchi
Yuna Naraoka
Taku Yamato
Akimi Ikeba
Kyoko Kumagai
Masahira Hattori
Chihiro Akazawa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1455753

1,145 views

Original Research

Published on 07 Apr 2025

Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation

in Gastrointestinal and Hepatic Pharmacology

Maycon Tavares Emílio-Silva
Vinicius Peixoto Rodrigues
Mariana Moraes Fioravanti
Antonio Jesús Ruiz-Malagon
Matheus Naia Fioretto
Priscila Romano Raimundo
Rie Ohara
Renata Assunção
Gabriela Bueno
Felipe Lima Dario

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567217

1,366 views

Original Research

Published on 04 Apr 2025

MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer

in Gastrointestinal and Hepatic Pharmacology

Jian Bi
Yufen Wang
Yingde Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523689

1,120 views

Original Research

Published on 04 Apr 2025

Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats

in Gastrointestinal and Hepatic Pharmacology

Yewen Sun
Yuchen Qu
Zhuan Yang
Bo Lv
Guanjun Wang
Kai Fan
Yuyuan Wang
Jie Pan
Ziyan Du
Yunli Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569856

951 views

Original Research

Published on 04 Apr 2025

Alpha-estradiol and (R)-(−)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex

in Gastrointestinal and Hepatic Pharmacology

Qiang Li
Pan Pan
Qingqing Xian
Jingtan Li
Jingting Wang
Jiaying Cai
Jing Wang
Yanfei Jia
Haiji Sun
Lulu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1492694

712 views

Original Research

Published on 03 Apr 2025

Paricalcitol alleviates intestinal ischemia-reperfusion injury via inhibition of the ATF4-CHOP pathway

in Gastrointestinal and Hepatic Pharmacology

Jiawei Zhang
Tingting Liu
Tongqing Xue
Zhongzhi Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529343

998 views

Brief Research Report

Published on 02 Apr 2025

Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity

in Gastrointestinal and Hepatic Pharmacology

Vidushi Tyagi
Ashish Kumar
Karuna Shanker
Anirban Pal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536683

1,498 views

Systematic Review

Published on 01 Apr 2025

Inflammatory bowel disease therapeutics: a bibliometric analysis of tofacitinib research in ulcerative colitis

in Gastrointestinal and Hepatic Pharmacology

Jianping Zhou
Yuting Xi
Yaping Zhang
Rui Zhang
Hao Fu
Ce Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570238

1,280 views

Systematic Review

Published on 28 Mar 2025

Research trends of nanomaterials in Helicobacter pylori: a bibliometric analysis from 2003 to 2023

in Gastrointestinal and Hepatic Pharmacology

Yeqing Lei
Tao Chen
Qin Du
Weihua Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546395

888 views

Review

Published on 27 Mar 2025

Mechanism and therapeutic potential of liver injury induced by cholesterol-associated proteins

in Gastrointestinal and Hepatic Pharmacology

Yourong Zhou
Yashi Cao
Yiming Yin
Zhifei Xu
Xiaochun Yang
Bo Yang
Peihua Luo
Hao Yan
Qiaojun He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572592

986 views
1 citation

Correction

Published on 27 Mar 2025

Corrigendum: Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway

in Gastrointestinal and Hepatic Pharmacology

Ju Huang
Jing Li
Zhijun Geng
Lixia Yin
Minzhu Niu
Qingqing Li
Xinyue Liu
Xinke Cheng
Xiaofeng Zhang
Xue Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1591086

676 views

Original Research

Published on 27 Mar 2025

Gut microbiota and HMGB1/NLRP3/GSDMD inflammasome-dependent pyroptosis: mechanisms by physcion ameliorates alcoholic liver fibrosis

in Gastrointestinal and Hepatic Pharmacology

Ting Bai
Hao-Lin Guo
Fei Wang
Yan-Yu Kang
Hao-Tian Zhang
Lu Dong
Yong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532590

1,797 views

Original Research

Published on 26 Mar 2025

Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital

in Gastrointestinal and Hepatic Pharmacology

Cai-Yun Long
Ying Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558897

748 views