Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Original Research

Published on 04 Dec 2020

Hepatoprotective Effect and Molecular Mechanisms of Hengshun Aromatic Vinegar on Non-Alcoholic Fatty Liver Disease

in Gastrointestinal and Hepatic Pharmacology

Shenghu Zhu
Linshu Guan
Xuemei Tan
Guoquan Li
Changjie Sun
Meng Gao
Bao Zhang
Lina Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2020.585582

5,118 views
10 citations

Original Research

Published on 30 Nov 2020

Inulin Exerts Beneficial Effects on Non-Alcoholic Fatty Liver Disease via Modulating gut Microbiome and Suppressing the Lipopolysaccharide-Toll-Like Receptor 4-Mψ-Nuclear Factor-κB-Nod-Like Receptor Protein 3 Pathway via gut-Liver Axis in Mice

in Gastrointestinal and Hepatic Pharmacology

Ting Bao
Fang He
Xiaoxia Zhang
Lili Zhu
Zhen Wang
Haixia Lu
Ting Wang
Yiwei Li
Shaoqi Yang
Hao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.558525

15,975 views
74 citations

Original Research

Published on 30 Nov 2020

Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice

in Gastrointestinal and Hepatic Pharmacology

Songtao Li
Qianyu Qian
Na Ying
Jianfei Lai
Luyan Feng
Sitong Zheng
Fusheng Jiang
Qing Song
Hui Chai
Xiaobing Dou

Frontiers in Pharmacology

doi 10.3389/fphar.2020.560905

9,037 views
57 citations

Original Research

Published on 30 Nov 2020

Adhesive Bacteria in the Terminal Ileum of Children Correlates With Increasing Th17 Cell Activation

in Gastrointestinal and Hepatic Pharmacology

Bo Chen
Diya Ye
Lingling Luo
Weirong Liu
Kerong Peng
Xiaoli Shu
Weizhong Gu
Xiaojun Wang
Charlie Xiang
Mizu Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.588560

3,505 views
14 citations

Original Research

Published on 30 Nov 2020

Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

in Gastrointestinal and Hepatic Pharmacology

Dongdong Wu
Peiyu Zhong
Yizhen Wang
Qianqian Zhang
Jianmei Li
Zhengguo Liu
Ailing Ji
Yanzhang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2020.585860

5,296 views
40 citations

Original Research

Published on 26 Nov 2020

Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis

in Gastrointestinal and Hepatic Pharmacology

Sichen Ren
Ying Wei
Ruilin Wang
Shizhang Wei
Jianxia Wen
Tao Yang
Xing Chen
Shihua Wu
Manyi Jing
Haotian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2020.600295

6,473 views
54 citations

Review

Published on 24 Nov 2020

Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols

in Gastrointestinal and Hepatic Pharmacology

Elvio Mazzotta
Egina Criseida Villalobos-Hernandez
Juan Fiorda-Diaz
Alan Harzman
Fievos L. Christofi

Frontiers in Pharmacology

doi 10.3389/fphar.2020.583422

51,093 views
102 citations

Original Research

Published on 23 Nov 2020

Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock

in Gastrointestinal and Hepatic Pharmacology

Youli Yao
Along Zuo
Qiyu Deng
Shikang Liu
Tianying Zhan
Maolin Wang
Haidong Xu
Junxian Ma
Yingying Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2020.573074

4,062 views
13 citations

Original Research

Published on 20 Nov 2020

Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway

in Gastrointestinal and Hepatic Pharmacology

Jiaqi Zhang
Xiaoqiang Liang
Jiacheng Li
Hao Yin
Fangchen Liu
Cheng Hu
Ling Li

Frontiers in Pharmacology

doi 10.3389/fphar.2020.549057

4,560 views
18 citations

Original Research

Published on 20 Nov 2020

A Close Relationship Between Networks of Interstitial Cells of Cajal and Gastrointestinal Transit In Vivo

in Gastrointestinal and Hepatic Pharmacology

Kazuhisa Kishi
Moe Kamizaki
Noriyuki Kaji
Satoshi Iino
Masatoshi Hori

Frontiers in Pharmacology

doi 10.3389/fphar.2020.587453

4,086 views
16 citations

Original Research

Published on 28 Oct 2020

Interleukin-4 Receptor α Subunit Deficiency Alleviates Murine Intestinal Inflammation In Vivo Through the Enhancement of Intestinal Mucosal Barrier Function

in Gastrointestinal and Hepatic Pharmacology

Ai Hertati
Shusaku Hayashi
Yudai Ogawa
Takeshi Yamamoto
Makoto Kadowaki

Frontiers in Pharmacology

doi 10.3389/fphar.2020.573470

3,351 views
11 citations

Original Research

Published on 20 Oct 2020

Mechanism of Paeoniflorin in the Treatment of Bile Duct Ligation-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology

in Gastrointestinal and Hepatic Pharmacology

Shizhang Wei
Xiao Ma
Ming Niu
Ruilin Wang
Tao Yang
Dan Wang
Jianxia Wen
Haotian Li
Yanling Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2020.586806

4,883 views
21 citations

Original Research

Published on 08 Oct 2020

Fecal Microbial Signatures Are Associated With Engraftment Failure Following Umbilical Cord Blood Transplantation in Pediatric Crohn’s Disease Patients With IL10RA Deficiency

in Gastrointestinal and Hepatic Pharmacology

Aijuan Xue
Xiaowen Qian
Xuefeng Gao
Ping Wang
Lin Wang
Cuifang Zheng
Zhiheng Huang
Wenhui Hu
Jieru Shi
Ying Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.580817

2,705 views
2 citations

Original Research

Published on 08 Oct 2020

Fish Oil, Cannabidiol and the Gut Microbiota: An Investigation in a Murine Model of Colitis

in Gastrointestinal and Hepatic Pharmacology

Cristoforo Silvestri
Ester Pagano
Sébastien Lacroix
Tommaso Venneri
Claudia Cristiano
Antonio Calignano
Olga A. Parisi
Angelo A. Izzo
Vincenzo Di Marzo
Francesca Borrelli

Frontiers in Pharmacology

doi 10.3389/fphar.2020.585096

11,789 views
53 citations

Review

Published on 02 Oct 2020

Intrahepatic TH17/TReg Cells in Homeostasis and Disease—It’s All About the Balance

in Gastrointestinal and Hepatic Pharmacology

Hannah K. Drescher
Lea M. Bartsch
Sabine Weiskirchen
Ralf Weiskirchen

Frontiers in Pharmacology

doi 10.3389/fphar.2020.588436

6,143 views
32 citations

Brief Research Report

Published on 02 Oct 2020

Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences

in Gastrointestinal and Hepatic Pharmacology

Lenka Jourová
Marketa Vavreckova
Nina Zemanova
Pavel Anzenbacher
Katerina Langova
Petra Hermanova
Tomas Hudcovic
Eva Anzenbacherova

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01303

4,901 views
18 citations