Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 01 Apr 2025

Dexmedetomidine alleviates lung ischemia-reperfusion injury by inhibiting cuproptosis: an in vivo study

in Inflammation Pharmacology

Hanqun Liu
Zicheng Wang
Tong Qiu
Wenxing Du
Zhe Wu
Sheng Chen
Wenjie Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562535

738 views

Original Research

Published on 27 Mar 2025

Homoplantaginin exerts therapeutic effects on intervertebral disc degeneration by alleviating TNF-α-induced nucleus pulposus cell senescence and inflammation

in Inflammation Pharmacology

Jiadong Guo
Pu Zhang
Xiao Yang
Xin Wang
Xiankun Cao
Jie Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526107

739 views

Original Research

Published on 26 Mar 2025

Senecio scandens Buch.-Ham. polysaccharides exert anti-atopic dermatitis effects by modulating gut microbiota and the MAPK/NF-κB pathway

in Inflammation Pharmacology

Zhi-Qin Hu
Shu-Shu Xie
Ming-Yuan Zhou
Yu-Chi Chen
Fang-Mei Zhou
Zhi-Shan Ding
Xiao-Qing Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573135

898 views

Original Research

Published on 25 Mar 2025

Phenylethyl isothiocyanate mitigates drug-induced liver injury in mice by inhibiting hepatocyte pyroptosis through the NLRP3-caspase-1-GSDMD pathway

in Inflammation Pharmacology

Ning An
Xiaoru Wang
Jia Qin
Meng Cheng
Mei Bai
Jingcai Cheng
Qiang Xu
Xuefeng Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539934

941 views

Review

Published on 21 Mar 2025

Cell death in acute lung injury: caspase-regulated apoptosis, pyroptosis, necroptosis, and PANoptosis

in Inflammation Pharmacology

Jun Xiao
Lichuan Wang
Bohan Zhang
Ana Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559659

1,967 views
1 citation

Original Research

Published on 20 Mar 2025

Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway

in Inflammation Pharmacology

Shengnan Shi
Jiaming Gao
Yehao Zhang
Min Zhan
Zhanfei Tan
Peili Wang
Jianhua Fu
Jianxun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535182

917 views

Mini Review

Published on 19 Mar 2025

Interplay between endogenous hormones and immune systems in human metapneumovirus pathogenesis and management

in Inflammation Pharmacology

Viviana A. Ruiz-Pozo
Santiago Cadena-Ullauri
Rafael Tamayo-Trujillo
Patricia Guevara-Ramírez
Elius Paz-Cruz
Mayra A. Castañeda Cataña
Ana Karina Zambrano

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568828

1,277 views
1 citation

Original Research

Published on 19 Mar 2025

Effect of anti-interleukin-5 antibody on development of vasculitis in an ovalbumin-induced eosinophilic vasculitis mouse model

in Inflammation Pharmacology

Kiyoto Kageyama
Eri Kikuchi
Nao Hoshino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546785

891 views

Review

Published on 18 Mar 2025

Ferroptosis and hyperoxic lung injury: insights into pathophysiology and treatment approaches

in Inflammation Pharmacology

Xiaoqiong Zhou
Lei Tian
Wenyan Xiong
Yulan Li
Qian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568246

965 views

Original Research

Published on 18 Mar 2025

The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout

in Inflammation Pharmacology

Zeng Zhang
Peng Wang
Tianyi Lei
Jianwei Guo
Yi Jiang
Yanhui Li
Jianxiong Zheng
Shunbing Wang
Haimuzi Xu
Guilin Jian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1480844

1,766 views
1 citation

Original Research

Published on 13 Mar 2025

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation

in Inflammation Pharmacology

Shuang Zheng
Yin Wang
Shuainan Tang
Yuntao Guo
Duan Ma
Xin Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549953

1,402 views
1 citation

Original Research

Published on 12 Mar 2025

Deciphering the role of IGFBP5 in delaying fibrosis and sarcopenia in aging skeletal muscle: therapeutic implications and molecular mechanisms

in Inflammation Pharmacology

Luze Shi
Zheci Ding
Jiwu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557703

1,321 views

Mini Review

Published on 12 Mar 2025

Salt-sensitive hypertension: role of endothelial and vascular dysfunction and sex

in Inflammation Pharmacology

Helen M. Butler
Marice K. McCrorey
Lada Palygina
Ryan Lacey
Justin P. Van Beusecum

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565962

1,217 views
1 citation

Brief Research Report

Published on 07 Mar 2025

Efficacy and safety of conventional disease-modifying antirheumatic drugs in VEXAS syndrome: real-world data from the international AIDA network

in Inflammation Pharmacology

Antonio Vitale
Flavia Leone
Valeria Caggiano
Andrea Hinojosa-Azaola
Eduardo Martín-Nares
Guillermo Arturo Guaracha-Basañez
Jiram Torres-Ruiz
Perla Ayumi Kawakami-Campos
Pravin Hissaria
Alicia Callisto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539756

1,862 views

Case Report

Published on 06 Mar 2025

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

in Inflammation Pharmacology

Nina Vidic Krhlikar
Matija Tomšič
Polona Jaki Mekjavić
Pia Klobučar
Nataša Vidović Valentinčič

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509404

882 views

Original Research

Published on 04 Mar 2025

Aspirin is associated with improved 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study based on MIMIC IV database

in Inflammation Pharmacology

Jianbao Wang
Xuemei Hu
Susu Cao
Yiwen Zhao
Mengting Chen
Tianfeng Hua
Min Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514392

2,070 views