Frontiers in Pharmacology | Integrative and Regenerative Pharmacology

Original Research

Published on 26 Jan 2023

Microtubule stabilization promotes the synthesis of type 2 collagen in nucleus pulposus cell by activating hippo-yap pathway

in Integrative and Regenerative Pharmacology

Xin Zhang
Shibin Shu
Zhenhua Feng
Yong Qiu
Hongda Bao
Zezhang Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1102318

3,421 views
4 citations

Review

Published on 06 Jan 2023

Extracellular vesicles derived from host and gut microbiota as promising nanocarriers for targeted therapy in osteoporosis and osteoarthritis

in Integrative and Regenerative Pharmacology

Kenneth Chat Pan Cheung
Ma Jiao
Chen Xingxuan
Jia Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1051134

6,455 views
12 citations

Review

Published on 06 Dec 2022

3D printing of bone and cartilage with polymer materials

in Integrative and Regenerative Pharmacology

Daoyang Fan
Yafei Liu
Yifan Wang
Qi Wang
Hao Guo
Yiming Cai
Ruipeng Song
Xing Wang
Weidong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044726

8,704 views
12 citations

Review

Published on 02 Dec 2022

Effect of vitamin K on wound healing: A systematic review and meta-analysis based on preclinical studies

in Integrative and Regenerative Pharmacology

Saiqing Tang
Zhen Ruan
Axue Ma
Dong Wang
Jiushe Kou

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1063349

11,324 views
14 citations

Review

Published on 29 Nov 2022

Primary cilia: The central role in the electromagnetic field induced bone healing

in Integrative and Regenerative Pharmacology

Yangmengfan Chen
Chao Lu
Xifu Shang
Kerong Wu
Kun Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1062119

3,485 views

Original Research

Published on 29 Nov 2022

Intra-articular injection of placental mesenchymal stromal cells ameliorates pain and cartilage anabolism/catabolism in knee osteoarthritis

in Integrative and Regenerative Pharmacology

Mengqiang Fan
Jingwen Zhang
Li Zhou
Zuxiang Chen
Ronghua Bao
Longpo Zheng
Peijian Tong
Yuhai Ma
Letian Shan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.983850

4,221 views
8 citations

Original Research

Published on 25 Nov 2022

Gene expression profiling in nucleus pulposus of human ruptured lumbar disc herniation

in Integrative and Regenerative Pharmacology

Xiaochun Li
Xueqiang Shen
Zhiqiang Wang
Hong Jiang
Zhijia Ma
Pengfei Yu
Zhenhan Yu
Xiang Qian
Jintao Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.892594

2,908 views
2 citations

Editorial

Published on 25 Nov 2022

Editorial: Methods and application in integrative and regenerative pharmacology: 2021

in Integrative and Regenerative Pharmacology

Peter Natesan Pushparaj
Gauthaman Kalamegam
Seeram Ramakrishna

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1077352

2,687 views

Correction

Published on 21 Nov 2022

Corrigendum: Pharmacological activity and clinical use of PDRN

in Integrative and Regenerative Pharmacology

Francesco Squadrito
Alessandra Bitto
Natasha Irrera
Gabriele Pizzino
Giovanni Pallio
Letteria Minutoli
Domenica Altavilla

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1073510

3,535 views
1 citation

Original Research

Published on 18 Nov 2022

Bushen huoxue decoction inhibits RANKL-stimulated osteoclastogenesis and glucocorticoid-induced bone loss by modulating the NF-κB, ERK, and JNK signaling pathways

in Integrative and Regenerative Pharmacology

Yamei Liu
Binlan Fu
Xiaoman Li
Chen Chen
Xican Li
Liangliang Xu
Bin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007839

3,115 views
5 citations

Review

Published on 15 Nov 2022

Serum and glucocorticoid-regulated kinase 1: Structure, biological functions, and its inhibitors

in Integrative and Regenerative Pharmacology

Hyunsoo Jang
Youngjun Park
Jaebong Jang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1036844

11,695 views
24 citations

Original Research

Published on 04 Nov 2022

First-in-human study to investigate the safety and pharmacokinetics of salvianolic acid A and pharmacokinetic simulation using a physiologically based pharmacokinetic model

in Integrative and Regenerative Pharmacology

Jinliang Chen
Zourong Ruan
Honggang Lou
Dandan Yang
Rong Shao
Yichao Xu
Xinhua Hu
Bo Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.907208

3,593 views
10 citations

Original Research

Published on 03 Nov 2022

Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NF-κB signaling pathway

in Integrative and Regenerative Pharmacology

Huan Yang
Xiao Yang
Kewei Rong
Jiarong Liang
Zhengting Wang
Jie Zhao
Pu Zhang
Yijie Li
Lihuan Wang
Hui Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2022.940475

3,502 views
23 citations

Original Research

Published on 26 Oct 2022

A multifunctional drug consisting of tetracycline conjugated with odanacatib for efficient periodontitis therapy

in Integrative and Regenerative Pharmacology

Dengke Li
Wuyang Zhang
Weiliang Ye
Yuan Liu
Yuan Li
Yiming Wang
Bingqing Shi
Xueni Zheng
Ying An
Zhen Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1046451

2,491 views
1 citation

Original Research

Published on 25 Oct 2022

Improved effect of fresh ginseng paste (radix ginseng-ziziphus jujube) on hyperuricemia based on network pharmacology and molecular docking

in Integrative and Regenerative Pharmacology

Hao Zhang
Wei Liu
Si-Min Qi
Jian-Feng Chi
Qiang Gao
Xiang-Hui Lin
Shen Ren
Zi Wang
Xiu-juan Lei
Wei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.955219

3,666 views
4 citations

Original Research

Published on 24 Oct 2022

Excessive sulfur oxidation in endoplasmic reticulum drives an inflammatory reaction of chondrocytes in aging mice

in Integrative and Regenerative Pharmacology

Kun Chen
Xianzuo Zhang
Zhi Li
Xingshi Yuan
Daijie Fu
Kerong Wu
Xifu Shang
Zhe Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1058469

1,707 views
2 citations