Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 23 Feb 2022

Genetic Epidemiology of Medication Safety and Efficacy Related Variants in the Central Han Chinese Population With Whole Genome Sequencing

in Pharmacogenetics and Pharmacogenomics

Junbo Tian
Jing Zhang
Zengguang Yang
Shuaisheng Feng
Shujuan Li
Shiqi Ren
Jianxiang Shi
Xinyue Hou
Xia Xue
Bei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.790832

3,351 views
4 citations

Brief Research Report

Published on 22 Feb 2022

560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment

in Pharmacogenetics and Pharmacogenomics

Mark A. Doll
David W. Hein

Frontiers in Pharmacology

doi 10.3389/fphar.2022.820082

1,942 views
3 citations

Original Research

Published on 22 Feb 2022

Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4

in Pharmacogenetics and Pharmacogenomics

Yuu Miyauchi
Akane Kimura
Madoka Sawai
Keiko Fujimoto
Yuko Hirota
Yoshitaka Tanaka
Shinji Takechi
Peter I. Mackenzie
Yuji Ishii

Frontiers in Pharmacology

doi 10.3389/fphar.2022.832931

7,255 views
4 citations

Review

Published on 18 Feb 2022

Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies

in Pharmacogenetics and Pharmacogenomics

Mohitosh Biswas
Nares Sawajan
Thanyada Rungrotmongkol
Kamonpan Sanachai
Maliheh Ershadian
Chonlaphat Sukasem

Frontiers in Pharmacology

doi 10.3389/fphar.2022.835136

17,839 views
20 citations

Review

Published on 10 Feb 2022

Pharmacogenetics in Primary Headache Disorders

in Pharmacogenetics and Pharmacogenomics

Irina I. Belyaeva
Anna G. Subbotina
Ivan I. Eremenko
Vadim V. Tarasov
Vladimir N. Chubarev
Helgi B. Schiöth
Jessica Mwinyi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.820214

8,780 views
17 citations

Review

Published on 24 Jan 2022

Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies

in Pharmacogenetics and Pharmacogenomics

Evangelia Eirini Tsermpini
Sara Redenšek
Vita Dolžan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.834129

7,491 views
15 citations

Systematic Review

Published on 21 Jan 2022

Do Genetic Polymorphisms Affect Fetal Hemoglobin (HbF) Levels in Patients With Sickle Cell Anemia Treated With Hydroxyurea? A Systematic Review and Pathway Analysis

in Pharmacogenetics and Pharmacogenomics

Rahyssa Rodrigues Sales
Bárbara Lisboa Nogueira
Jéssica Abdo Gonçalves Tosatti
Karina Braga Gomes
Marcelo Rizzatti Luizon

Frontiers in Pharmacology

doi 10.3389/fphar.2021.779497

9,280 views
20 citations

Review

Published on 21 Jan 2022

Elucidation of Cellular Contributions to Heparin-Induced Thrombocytopenia Using Omic Approaches

in Pharmacogenetics and Pharmacogenomics

Jason B. Giles
Elise C. Miller
Heidi E. Steiner
Jason H. Karnes

Frontiers in Pharmacology

doi 10.3389/fphar.2021.812830

5,050 views
4 citations

Brief Research Report

Published on 18 Jan 2022

DBP rs7041 and DHCR7 rs3829251 are Linked to CD4+ Recovery in HIV Patients on Antiretroviral Therapy

in Pharmacogenetics and Pharmacogenomics

Salvador Resino
María Ángeles Jiménez-Sousa
Julià Blanco
Yolanda M. Pacheco
Jorge del Romero
Joaquim Peraire
Ana Virseda-Berdices
María José Muñoz-Gómez
Carlos Galera-Peñaranda
Lucio Jesus García-Fraile

Frontiers in Pharmacology

doi 10.3389/fphar.2021.773848

2,783 views
1 citation

Editorial

Published on 18 Jan 2022

Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs

in Pharmacogenetics and Pharmacogenomics

Youssef Daali
Amin Rostami-Hodjegan
Caroline F. Samer

Frontiers in Pharmacology

doi 10.3389/fphar.2021.834717

1,945 views
1 citation

Editorial

Published on 11 Jan 2022

Editorial: Pharmacogenetics and Pharmacogenomics in Latin America: Ethnic Variability, New Insights in Advances and Perspectives: A RELIVAF-CYTED Initiative

in Pharmacogenetics and Pharmacogenomics

Patricia Esperón
Matías F. Martínez
María A. Redal
Alberto Lazarowski
Andrés López-Cortés
Nelson M. Varela
Luis A. Quiñones

Frontiers in Pharmacology

doi 10.3389/fphar.2021.833000

2,353 views
5 citations

Brief Research Report

Published on 05 Jan 2022

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

in Pharmacogenetics and Pharmacogenomics

Stella Trompet
Iris Postmus
Helen R. Warren
Raymond Noordam
Roelof A. J. Smit
Elizabeth Theusch
Xiaohui Li
Benoit Arsenault
Daniel I. Chasman
Graham A. Hitman

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679857

4,164 views
4 citations

Original Research

Published on 03 Jan 2022

Human Arylamine N-Acetyltransferase 1 (NAT1) Knockout in MDA-MB-231 Breast Cancer Cell Lines Leads to Transcription of NAT2

in Pharmacogenetics and Pharmacogenomics

Samantha M. Carlisle
Patrick J. Trainor
Mark A. Doll
David W. Hein

Frontiers in Pharmacology

doi 10.3389/fphar.2021.803254

3,337 views
9 citations

Original Research

Published on 20 Dec 2021

Neuropsychiatric Adverse Events of Montelukast: An Analysis of Real-World Datasets and drug−gene Interaction Network

in Pharmacogenetics and Pharmacogenomics

Ryogo Umetsu
Mizuki Tanaka
Yoko Nakayama
Yamato Kato
Natsumi Ueda
Yuri Nishibata
Shiori Hasegawa
Kiyoka Matsumoto
Noriaki Takeyama
Kazuhiro Iguchi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.764279

18,638 views
13 citations

Review

Published on 09 Dec 2021

Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor

in Pharmacogenetics and Pharmacogenomics

Qing-Yan Yang
Ya-Hui Hu
Hong-Li Guo
Ying Xia
Yong Zhang
Wei-Rong Fang
Yun-Man Li
Jing Xu
Feng Chen
Yong-Ren Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.771487

9,853 views
18 citations

Original Research

Published on 06 Dec 2021

Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer

in Pharmacogenetics and Pharmacogenomics

Taraswi Mitra Ghosh
Jason White
Joshua Davis
Suman Mazumder
Teeratas Kansom
Elena Skarupa
Grafton S. Barnett
Gary A. Piazza
R. Curtis Bird
Amit K. Mitra

Frontiers in Pharmacology

doi 10.3389/fphar.2021.736951

5,217 views
8 citations