Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 13 Aug 2021

Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data

in Pharmacogenetics and Pharmacogenomics

Albert Martínez-Pinteño
Patricia Gassó
Llucia Prohens
Alex G. Segura
Mara Parellada
Jerónimo Saiz-Ruiz
Manuel J. Cuesta
Miguel Bernardo
Amalia Lafuente
Sergi Mas

Frontiers in Pharmacology

doi 10.3389/fphar.2021.729474

5,766 views
3 citations

Original Research

Published on 26 Jul 2021

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B15:02 and HLA-A31:01 Across Diverse Ancestral Backgrounds

in Pharmacogenetics and Pharmacogenomics

Amanda Buchner
Xiuying Hu
Katherine J. Aitchison

Frontiers in Pharmacology

doi 10.3389/fphar.2021.713178

5,856 views
3 citations

Brief Research Report

Published on 23 Jul 2021

CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region

in Pharmacogenetics and Pharmacogenomics

Paula Ferreira Salles
Daiana Souza Perce-da-Silva
Atila Duque Rossi
Luisa Riehl Raposo
Aina Danaisa Ramirez Ramirez
Otílio Machado Pereira Bastos
Lilian Rose Pratt-Riccio
Gustavo Capatti Cassiano
Andrea Regina Souza Baptista
Cynthia Chester Cardoso

Frontiers in Pharmacology

doi 10.3389/fphar.2021.542342

2,906 views
3 citations

Original Research

Published on 16 Jul 2021

Mutational Characteristics of Causative Genes in Chinese Hereditary Spherocytosis Patients: a Report on Fourteen Cases and a Review of the Literature

in Pharmacogenetics and Pharmacogenomics

Dong Wang
Li Song
Li Shen
Kaihui Zhang
Yuqiang Lv
Min Gao
Jian Ma
Ya Wan
Zhongtao Gai
Yi Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.644352

4,209 views
23 citations

Review

Published on 14 Jul 2021

Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone

in Pharmacogenetics and Pharmacogenomics

Paula Soria-Chacartegui
Gonzalo Villapalos-García
Pablo Zubiaur
Francisco Abad-Santos
Dora Koller

Frontiers in Pharmacology

doi 10.3389/fphar.2021.711940

19,475 views
42 citations

Original Research

Published on 12 Jul 2021

A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China

in Pharmacogenetics and Pharmacogenomics

Chengxian Guo
Biwen Hu
Chengjun Guo
Xiangguang Meng
Yun Kuang
Longjian Huang
Danling Wang
Kangwei Xu
Yanlin Zhao
Guoping Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.682020

5,700 views
23 citations

Original Research

Published on 09 Jul 2021

The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy

in Pharmacogenetics and Pharmacogenomics

Shitao Wang
Liang Zhou
Chenglu He
Dan Wang
Xuemei Cai
Yanying Yu
Liling Chen
Di Lu
Ligong Bian
Sunbing Du

Frontiers in Pharmacology

doi 10.3389/fphar.2021.701575

3,167 views
5 citations

Brief Research Report

Published on 05 Jul 2021

CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients

in Pharmacogenetics and Pharmacogenomics

Yilei Yang
Xin Huang
Yinping Shi
Rui Yang
Haiyan Shi
Xinmei Yang
Guoxiang Hao
Yi Zheng
Jianning Wang
Lequn Su

Frontiers in Pharmacology

doi 10.3389/fphar.2021.692922

4,971 views
8 citations

Review

Published on 28 Jun 2021

Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

in Pharmacogenetics and Pharmacogenomics

Meike Kaehler
Ingolf Cascorbi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.696960

5,815 views
29 citations

Original Research

Published on 28 Jun 2021

Pharmacogenomics Implementation Training Improves Self-Efficacy and Competency to Drive Adoption in Clinical Practice

in Pharmacogenetics and Pharmacogenomics

Fadhli Adesta
Caroline Mahendra
Kathleen Irena Junusmin
Arya Melissa Selva Rajah
Sharon Goh
Levana Sani
Alexandre Chan
Astrid Irwanto

Frontiers in Pharmacology

doi 10.3389/fphar.2021.684907

4,064 views
11 citations

Mini Review

Published on 21 Jun 2021

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity

in Pharmacogenetics and Pharmacogenomics

L. McEvoy
D. F. Carr
M. Pirmohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2021.684162

26,793 views
54 citations

Brief Research Report

Published on 16 Jun 2021

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

in Pharmacogenetics and Pharmacogenomics

Myriam El Biali
Rudolf Karch
Cécile Philippe
Helmuth Haslacher
Nicolas Tournier
Marcus Hacker
Markus Zeitlinger
Doreen Schmidl
Oliver Langer
Martin Bauer

Frontiers in Pharmacology

doi 10.3389/fphar.2021.698966

3,379 views
6 citations

Correction

Published on 10 Jun 2021

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

in Pharmacogenetics and Pharmacogenomics

Junling Wang
Zhimei Liu
Manting Xu
Xiaodi Han
Changhong Ren
Xinying Yang
Chunhua Zhang
Fang Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.686933

1,454 views

Original Research

Published on 09 Jun 2021

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

in Pharmacogenetics and Pharmacogenomics

Stefan Wolking
Ciarán Campbell
Caragh Stapleton
Mark McCormack
Norman Delanty
Chantal Depondt
Michael R. Johnson
Bobby P. C. Koeleman
Roland Krause
Wolfram S. Kunz

Frontiers in Pharmacology

doi 10.3389/fphar.2021.688386

7,770 views
14 citations

Review

Published on 09 Jun 2021

From Genome to Drugs: New Approaches in Antimicrobial Discovery

in Pharmacogenetics and Pharmacogenomics

Federico Serral
Florencia A. Castello
Ezequiel J. Sosa
Agustín M. Pardo
Miranda Clara Palumbo
Carlos Modenutti
María Mercedes Palomino
Alberto Lazarowski
Jerónimo Auzmendi
Pablo Ivan P. Ramos

Frontiers in Pharmacology

doi 10.3389/fphar.2021.647060

13,235 views
36 citations

Original Research

Published on 07 Jun 2021

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

in Pharmacogenetics and Pharmacogenomics

Mingkun Guo
Shihai Li
Yifan Zhou
Menglong Li
Zhining Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.658072

2,960 views
4 citations

Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B*15:02 and HLA-A*31:01 Across Diverse Ancestral Backgrounds

CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region

Mutational Characteristics of Causative Genes in Chinese Hereditary Spherocytosis Patients: a Report on Fourteen Cases and a Review of the Literature

Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone

A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China

The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy

CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients

Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

Pharmacogenomics Implementation Training Improves Self-Efficacy and Competency to Drive Adoption in Clinical Practice

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

From Genome to Drugs: New Approaches in Antimicrobial Discovery

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B15:02 and HLA-A31:01 Across Diverse Ancestral Backgrounds