Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 02 Feb 2024

Measurement of CYP1A2 and CYP3A4 activity by a simplified Geneva cocktail approach in a cohort of free-living individuals: a pilot study

in Pharmacogenetics and Pharmacogenomics

Constance A. Sobsey
Noor Mady
Vincent R. Richard
Andre LeBlanc
Thomas Zakharov
Christoph H. Borchers
R. Thomas Jagoe

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1232595

2,693 views
1 citation

Original Research

Published on 31 Jan 2024

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

in Pharmacogenetics and Pharmacogenomics

Lei Feng
Rui Wang
Qian Zhao
Jun Wang
Gang Luo
Chongwen Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1320028

2,572 views
2 citations

Review

Published on 30 Jan 2024

Advances in the study of marketed antibody-drug Conjugates (ADCs) for the treatment of breast cancer

in Pharmacogenetics and Pharmacogenomics

Yan Liang
Purong Zhang
Feng Li
Houyun Lai
Tingting Qi
Yixin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1332539

5,844 views
3 citations

Mini Review

Published on 24 Jan 2024

Precision medicine: a new era for inner ear diseases

in Pharmacogenetics and Pharmacogenomics

Elisa Tavazzani
Paolo Spaiardi
Donatella Contini
Giulio Sancini
Giancarlo Russo
Sergio Masetto

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1328460

3,788 views
3 citations

Review

Published on 19 Jan 2024

Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine

in Pharmacogenetics and Pharmacogenomics

Ibraheem Dakilah
Amani Harb
Eman Abu-Gharbieh
Waseem El-Huneidi
Jalal Taneera
Rifat Hamoudi
Mohammed H. Semreen
Yasser Bustanji

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1324001

4,356 views
10 citations

Review

Published on 09 Jan 2024

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

in Pharmacogenetics and Pharmacogenomics

Alessia Mondello
Michele Dal Bo
Giuseppe Toffoli
Maurizio Polano

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1260276

5,381 views
5 citations

Original Research

Published on 08 Jan 2024

CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation

in Pharmacogenetics and Pharmacogenomics

Nathan D. Seligson
Xunjie Zhang
Mark C. Zemanek
Jasmine A. Johnson
Zachary VanGundy
Danxin Wang
Mitch A. Phelps
Julianna Roddy
Craig C. Hofmeister
Junan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1334440

1,979 views
2 citations

Original Research

Published on 03 Jan 2024

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

in Pharmacogenetics and Pharmacogenomics

Huaqiang Bi
Kai Feng
Xiaofei Wang
Ping Zheng
Chengming Qu
Kuansheng Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304996

1,527 views

Case Report

Published on 03 Jan 2024

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

in Pharmacogenetics and Pharmacogenomics

Olga Rogozina
Carmen Ruiz-Fernández
Susana Martín-López
Ibtissam Akatbach-Bousaid
Miguel González-Muñoz
Elena Ramírez

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293294

2,383 views
3 citations

Review

Published on 12 Dec 2023

Stilbenes: a promising small molecule modulator for epigenetic regulation in human diseases

in Pharmacogenetics and Pharmacogenomics

Jing Tian
Li Jin
Hongquan Liu
Zichun Hua

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326682

3,144 views
11 citations

Review

Published on 11 Dec 2023

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

in Pharmacogenetics and Pharmacogenomics

Alessia Greco
Francesca Coperchini
Laura Croce
Flavia Magri
Marsida Teliti
Mario Rotondi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1303844

3,749 views
7 citations

Review

Published on 01 Dec 2023

Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations

in Pharmacogenetics and Pharmacogenomics

Sahar M. Altoum
Zeina N. Al-Mahayri
Bassam R. Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1286494

4,090 views
1 citation

Original Research

Published on 28 Nov 2023

miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

in Pharmacogenetics and Pharmacogenomics

Nadine De Godoy Torso
Julia Coelho França Quintanilha
Maria Aparecida Cursino
Eder De Carvalho Pincinato
Pía Loren
Luis A. Salazar
Carmen Silvia Passos Lima
Patricia Moriel

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1275238

1,943 views
5 citations

Original Research

Published on 22 Nov 2023

Single-nucleotide polymorphism profiling by multimodal-targeted next-generation sequencing in methotrexate-resistant and -sensitive human osteosarcoma cell lines

in Pharmacogenetics and Pharmacogenomics

Chiara Casotti
Claudia Maria Hattinger
Maria Pia Patrizio
Silvia Luppi
Leonardo Fantoni
Michela Pasello
Katia Scotlandi
Toni Ibrahim
Massimo Serra

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1294873

2,139 views

Brief Research Report

Published on 17 Nov 2023

Pharmacogenetics of pediatric acute lymphoblastic leukemia in Uruguay: adverse events related to induction phase drugs

in Pharmacogenetics and Pharmacogenomics

Gabriela Burgueño-Rodríguez
Yessika Méndez
Natalia Olano
Magdalena Schelotto
Luis Castillo
Ana María Soler
Julio da Luz

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1278769

2,824 views
2 citations

Original Research

Published on 15 Nov 2023

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

in Pharmacogenetics and Pharmacogenomics

Eun Jeong Jang
Jung Sun Kim
Seo A. Choi
Jeong Yee
Tae-Jin Song
Junbeom Park
Hye Sun Gwak

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1290785

1,547 views
1 citation